Protein Alignment PDCD2 and Zfrp8

DIOPT Version :10

• Sequence 1: NP_002589.2
• Gene: PDCD2 / 5134
• HGNCID: 8762
• Length: 344
• Species: Homo sapiens
• Sequence 2: NP_611890.1
• Gene: Zfrp8 / 45021
• FlyBaseID: FBgn0021875
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 143/358 - (39%)
• Similarity: 192/358 - (53%)
• Gaps: 45/358 - (12%)

Human     9 VELGFAESAP--AWRLRSEQFPSKVGGRPAWLGAAGLPGPQALACELCGRPLSFLLQVYAPLPGR 71
            ::|||||.:.  || |.:..||||:||:||||....||....|.|..|..|.|||.|:|||....
  Fly     3 IDLGFAEKSDNGAW-LSNRYFPSKLGGQPAWLELEALPPTSQLQCSKCRAPKSFLAQLYAPFEDE 66

Human    72 PDAFHRCIFLFCCREQPC-----CAGLRVFRNQLPRKNDFYSYEPPSE--NPPPETGESVCLQLK 129
            .: |||.|::|.||...|     .:...|.|:||||||.|:|.|.||:  .|.|..   .||:
  Fly    67 YN-FHRSIYVFLCRNSDCQEAQNASNFTVLRSQLPRKNKFFSEEEPSDVGQPLPAV---PCLK-- 125

Human   130 SGAHLCRVCGCLGPKTCSRCHKAYYCSKEHQTLDWRLGHKQACAQPDHLDHIIPDHNFLFPEFEI 194
               .||..|||..|..||:|...:|||.|||...|. .||..|..|:.... .|....:||||||
  Fly   126 ---KLCAACGCHAPHACSKCKAIHYCSPEHQRAHWP-QHKPNCGAPEVATE-KPLTQIVFPEFEI 185

Human   195 V-----IETEDEIMPEVVEKEDYSEI-----IGSMGEALEEELDS-MAKHESREDKIFQKFKTQI 248
            |     :|:.:|...:.....::.|:     .|.:....|.|:|. .....:.:||.|::||.|.
  Fly   186 VMDSNPVESGEEDKDDEARLAEFQELESSGKTGDLSNVSEAEMDKYFGNSAAADDKTFRQFKKQT 250

Human   249 ALEPEQILRYGRGIAPIWISG-----ENIPQEKDIPDC-PCGAKRILEFQVMPQLLNYLKADRLG 307
            |.||:||:||.||..|:||:.     |:  |...:|:| .||.:|..|||:|||.|..|:.:.|
  Fly   251 AAEPDQIVRYKRGGQPLWITNTVKTVED--QLNKLPNCIACGGERQFEFQIMPQALTLLEDENL- 312

Human   308 KSIDWGILAVFTCAESCSLGTGYTEEFVWKQDV 340
               |||:|||:|||:||.: .||.||.:.|||:
  Fly   313 ---DWGVLAVYTCAKSCPI-DGYVEELLIKQDI 341

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PDCD2	NP_002589.2	zf-MYND	135..172	CDD:460312	17/36 (47%)
		PDCD2_C	238..339	CDD:461221	50/106 (47%)
Zfrp8	NP_611890.1	zf-MYND	128..164	CDD:460312	17/36 (47%)
		PDCD2_C	240..340	CDD:461221	50/106 (47%)