Protein Alignment CDK18 and Eip63E

DIOPT Version :9

• Sequence 1: XP_016856912.1
• Gene: CDK18 / 5129
• HGNCID: 8751
• Length: 572
• Species: Homo sapiens
• Sequence 2: NP_001261373.1
• Gene: Eip63E / 38433
• FlyBaseID: FBgn0005640
• Length: 538
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 228/503 - (45%)
• Similarity: 299/503 - (59%)
• Gaps: 40/503 - (7%)

Human    74 MKNFKRRFSLSVPRTETIEESLAEFTEQFNQLHNRRNENLQLGPLGRDPPQECSTFSPTDSGEEP 138
            ::..|:|.|.|..|.....|...|.|...:..|:.|.     |..|.........::..:|.|..
  Fly    30 LQKLKKRLSHSFGRLTISREDGDESTHHHHHHHHHRG-----GHGGHHNHGNKVPYNGYNSEEYL 89

Human   139 GQLSPGVQFQRRQNQRRFSMEVRA--SGALPRQVAGCTHKGVHRRAAALQPDFDVSKRLS----- 196
            .:|.|.......:...|:..:..|  ....|:..........|.|         |.::||
  Fly    90 DRLEPNGNIPADKTNCRYGAQESAKNDNNKPQDWRSTDSTDHHDR---------VQRQLSVSSDS 145

Human   197 --LPMDIRLPQEFLQKLQMESPDLPKPLSRM--------SRRASLSDIG----FGKLETYVKLDK 247
              |..|||...::...:.|.....|:|.|.:        .||...|..|    |||.|.||||:.
  Fly   146 KLLDEDIREEMKYHSHVVMRPKKPPRPKSEVFLNKQETHPRRKRFSAFGGDSPFGKQEAYVKLEP 210

Human   248 LGEGTYATVFKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKNLKHANIVTLHDLIHTDRS 312
            ||||:||||:||.||||...||||||||:.|||||.|||||.||||.|||:|||||||::||..:
  Fly   211 LGEGSYATVYKGFSKLTYQRVALKEIRLQEEEGAPFTAIREASLLKELKHSNIVTLHDIVHTRET 275

Human   313 LTLVFEYLDSDLKQYLD-HCGNLMSMHNVKIFMFQLLRGLAYCHHRKILHRDLKPQNLLINERGE 376
            ||.||||:::||.||:: |.|.| ...||::|:|||||||:|||.|::||||:|||||||::.||
  Fly   276 LTFVFEYVNTDLSQYMEKHPGGL-DHRNVRLFLFQLLRGLSYCHKRRVLHRDVKPQNLLISDCGE 339

Human   377 LKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPG 441
            |||||||||||||||:.|||:|||||||||||||||||||||.:||||||||..||.||.|.|||
  Fly   340 LKLADFGLARAKSVPSHTYSHEVVTLWYRPPDVLLGSTEYSTSLDMWGVGCIFVEMVTGMPTFPG 404

Human   442 -STVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYSFPCYLPQPLINHAPRL--DTDGIHLLSSL 503
             ....::|..||:|||||||:||||||.|..::.:....|.|:.|.::.|||  ..:|..:.:..
  Fly   405 IRDTYDQLDKIFKLLGTPTEDTWPGVTHFPGYKPHKLGFYRPRKLGHNFPRLYDIIEGETIANGF 469

Human   504 LLYESKSRMSAEAALSHSYFRSLGERVHQLEDTASIFSLKEIQLQKDP 551
            |....:.|:.|:.||.|.||..|.:::::|.|..|||:::.:||..:|
  Fly   470 LQLNPEQRLGADDALQHPYFAQLPKKLYELPDETSIFTVEGVQLYTEP 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK18	XP_016856912.1	None
Eip63E	NP_001261373.1	PLN00009	203..492	CDD:177649	180/289 (62%)
		STKc_PCTAIRE_like	204..489	CDD:270835	177/285 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0594
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1010560at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.820