DRSC/TRiP Functional Genomics Resources

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Protein Alignment CDK17 and PHO85

DIOPT Version :9

Sequence 1:NP_001163935.1 Gene:CDK17 / 5128 HGNCID:8750 Length:523 Species:Homo sapiens
Sequence 2:NP_015294.1 Gene:PHO85 / 856076 SGDID:S000005952 Length:305 Species:Saccharomyces cerevisiae


Alignment Length:297 Identity:155/297 - (52%)
Similarity:205/297 - (69%) Gaps:25/297 - (8%)


- Green bases have known domain annotations that are detailed below.


Human   194 KLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVH 258
            :|||||.|||||||||.:|.|...|||||::|:.|||.|.|||||:||:|:|||.|||.|:|::|
Yeast     9 QLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIH 73

Human   259 TDKSLTLVFEYLDKDLKQYMDD--CGNI---MSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQN 318
            |:..||||||::|.|||:|||.  .||.   :.::.||.|.:|:|:|||:||..|:|||||||||
Yeast    74 TENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQN 138

Human   319 LLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMA 383
            ||||::|:|||.|||||||..:|..|:|:||||||||.||||:||..|||.||:|..|||..||.
Yeast   139 LLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMI 203

Human   384 SGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKP-----------QPLIN 437
            :|:|||||:..|::|.|||.::|||::..||.::        ..|||.|           |.|..
Yeast   204 TGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVT--------KLPKYNPNIQQRPPRDLRQVLQP 260

Human   438 HAPR-LDSEGIELITKFLQYESKKRVSAEEAMKHVYF 473
            |... ||...::.:...||.....|:||::|:.|.:|
Yeast   261 HTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CDK17NP_001163935.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 30..55
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 103..123
STKc_PCTAIRE2 185..493 CDD:143377 155/297 (52%)
PHO85NP_015294.1 PKc_like 6..297 CDD:419665 154/295 (52%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG0594
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24056
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.910

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