Protein Alignment CDK17 and PHO85

DIOPT Version :10

• Sequence 1: NP_002586.2
• Gene: CDK17 / 5128
• HGNCID: 8750
• Length: 523
• Species: Homo sapiens
• Sequence 2: NP_015294.1
• Gene: PHO85 / 856076
• SGDID: S000005952
• Length: 305
• Species: Saccharomyces cerevisiae
• Alignment Length: 297
• Identity: 155/297 - (52%)
• Similarity: 205/297 - (69%)
• Gaps: 25/297 - (8%)

Human   194 KLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHEEGAPCTAIREVSLLKDLKHANIVTLHDIVH 258
            :|||||.|||||||||.:|.|...|||||::|:.|||.|.|||||:||:|:|||.|||.|:|::|
Yeast     9 QLEKLGNGTYATVYKGLNKTTGVYVALKEVKLDSEEGTPSTAIREISLMKELKHENIVRLYDVIH 73

Human   259 TDKSLTLVFEYLDKDLKQYMDD--CGNI---MSMHNVKLFLYQILRGLAYCHRRKVLHRDLKPQN 318
            |:..||||||::|.|||:|||.  .||.   :.::.||.|.:|:|:|||:||..|:|||||||||
Yeast    74 TENKLTLVFEFMDNDLKKYMDSRTVGNTPRGLELNLVKYFQWQLLQGLAFCHENKILHRDLKPQN 138

Human   319 LLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYSTQIDMWGVGCIFFEMA 383
            ||||::|:|||.|||||||..:|..|:|:||||||||.||||:||..|||.||:|..|||..||.
Yeast   139 LLINKRGQLKLGDFGLARAFGIPVNTFSSEVVTLWYRAPDVLMGSRTYSTSIDIWSCGCILAEMI 203

Human   384 SGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYNFPKYKP-----------QPLIN 437
            :|:|||||:..|::|.|||.::|||::..||.::        ..|||.|           |.|..
Yeast   204 TGKPLFPGTNDEEQLKLIFDIMGTPNESLWPSVT--------KLPKYNPNIQQRPPRDLRQVLQP 260

Human   438 HAPR-LDSEGIELITKFLQYESKKRVSAEEAMKHVYF 473
            |... ||...::.:...||.....|:||::|:.|.:|
Yeast   261 HTKEPLDGNLMDFLHGLLQLNPDMRLSAKQALHHPWF 297

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDK17	NP_002586.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..55
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..123
		STKc_PCTAIRE2	185..493	CDD:143377	155/297 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	501..523
PHO85	NP_015294.1	Protein Kinases, catalytic domain	6..297	CDD:473864	154/295 (52%)