Protein Alignment CDKL3 and taok1

DIOPT Version :9

• Sequence 1: XP_011541731.1
• Gene: CDKL3 / 51265
• HGNCID: 15483
• Length: 619
• Species: Homo sapiens
• Sequence 2: NP_001116260.1
• Gene: taok1 / 733788
• XenbaseID: XB-GENE-956111
• Length: 1001
• Species: Xenopus tropicalis
• Alignment Length: 651
• Identity: 157/651 - (24%)
• Similarity: 253/651 - (38%)
• Gaps: 156/651 - (23%)

Human     2 EMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNK--IAMREIKFLKQFHHENLVN 64
            :::..|.::|.||:|.|.......|.::||||......:||..|  ..::|:|||::..|.|.:.
 Frog    26 KLFSDLREIGHGSFGAVYFAHDARTSEVVAIKKMSYSGKQSNEKWQDIIKEVKFLQRIKHPNSIE 90

Human    65 LIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPE 129
            ....:.::....||.|:...:..|.|:.:...|:...:.......|:.:.||||:|:||||||..
 Frog    91 YKGCYLREHTAWLVMEYCLGSASDLLEVHKKPLQEIEIAAITHGALQGLAYLHSHNLIHRDIKAG 155

Human   130 NILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKYVYFGILSAFPRPV 194
            |||:::.|..||.|||.| ::.:|.:   .:|.|.::.|||::|. ...|:|         ...|
 Frog   156 NILLTEPGQVKLADFGSA-SIVSPAN---SFVGTPYWMAPEVILA-MDEGQY---------DGKV 206

Human   195 DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKN 259
            |:|:||...||:|...|.|.:.:.:..|:.|   ..|.||.||:                    |
 Frog   207 DVWSLGITCIELAERKPPLFNMNAMSALYHI---AQNESPTLQS--------------------N 248

Human   260 ARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPE-------------- 310
            ....|      ..:.|.:|||..|.||.:|.:||.|.:..|:      .||
 Frog   249 EWSDY------FRNFVDSCLQKIPQDRPTSDELLKHMFVLRE------RPETVLIDLIQRTKDAV 301

Human   311 ----------LKAKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSS-SVLGKEIEKEKK 364
                      :|..|.|||.....::.:|..:|.|.......||  |::.|: |:....|....:
 Frog   302 RELDNLQYRKMKKLLFQEAHNGPAVETQEEEEEQEHGVGRTGTV--NSIGSNQSIPSMSISASSQ 364

Human   365 PKEIKVRVIKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNG 429
            ...:        ....|.|:.|        .:.|..|..|.:..::.::.::|.....|.
 Frog   365 SSSV--------NSLPDASDDK--------SELDMMEGDHTVMSNSSVIHLKPEEESYPE----- 408

Human   430 LKENPHCGGSVTMPPINLTNSNLMAANLSSNLFHPS-VRLTERAKKRRTSSQSIGQVMPNSRQED 493
             :..|....|....|..::.             |.| .|..|.....||:|....|:   ...|.
 Frog   409 -EPEPRARPSEPQSPPQVSR-------------HKSHYRNREHFATIRTASLVTRQI---QEHEQ 456

Human   494 PGPIQSQMEKGIFNERTGHSDQ-MANENKRKLNFS----RSDR----KEFHFPELPVTIQSKDTK 549
            ...::.|| .|....|..|..| ||.|||.|....    |.|:    :..:|......:..|...
 Frog   457 DSELREQM-SGYKRMRRQHQKQLMALENKLKAEMDEHRLRLDKDLETQRNNFAAEMEKLVKKHQA 520

Human   550 GMEVKQIKMLKRESKK----------------TESSK---------IPTLLNVDQN---QEKQEF 586
            .|| |::|::..|.||                .||.|         :...||.:|:   :||||:
 Frog   521 AME-KELKLMANEEKKFQQHIQAQQKKELNSFLESQKREYKLRKEQLKEELNENQSTPKKEKQEW 584

Human   587 I 587
            :
 Frog   585 L 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL3	XP_011541731.1	STKc_CDKL2_3	2..298	CDD:270836	87/297 (29%)
taok1	NP_001116260.1	STKc_TAO1	2..318	CDD:270805	92/340 (27%)
		SbcC	<444..>876	CDD:223496	36/147 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910