Protein Alignment CDKL3 and CG7236

DIOPT Version :9

• Sequence 1: XP_011541731.1
• Gene: CDKL3 / 51265
• HGNCID: 15483
• Length: 619
• Species: Homo sapiens
• Sequence 2: NP_608950.3
• Gene: CG7236 / 33798
• FlyBaseID: FBgn0031730
• Length: 438
• Species: Drosophila melanogaster
• Alignment Length: 329
• Identity: 145/329 - (44%)
• Similarity: 194/329 - (58%)
• Gaps: 29/329 - (8%)

Human     1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYE-RPEQSVNKIAMREIKFLKQFHHENLVN 64
            |:.||.|.::||||||.|.||:.:.||.:||:|.|.| ..:.::.|||:|||:.||...|.|||:
  Fly    47 MDRYEKLSRLGEGSYGVVYKCRDRETGALVAVKRFVESEDDPAIRKIALREIRLLKNLKHPNLVS 111

Human    65 LIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPE 129
            |:||||:|:::||||||.:.|||.||:.:..|......::..:|.|..:.|.|....:|||||||
  Fly   112 LLEVFRRKRRLHLVFEFCELTVLHELERHPQGCPEHLTKQICYQTLLGVAYCHKQGCLHRDIKPE 176

Human   130 NILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKYVYFGILSAFPRPV 194
            |||::..|..|||||||||.| :||:.|||||||||||||||::.||.||            .||
  Fly   177 NILLTAQGQVKLCDFGFARML-SPGENYTDYVATRWYRAPELLVGDTQYG------------TPV 228

Human   195 DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSP-HLQNIFSKSPIFAGVVLPQVQHPK 258
            |:||:||:..|:..|....|..||:|.|:.|...:|:|.| |:| ||.::..|.|:.||.....:
  Fly   229 DVWAIGCLFAELVRGEALWPGRSDVDQLYLIRKTLGDLLPRHIQ-IFGQNEYFKGITLPVPPTLE 292

Human   259 NARKKYP---KLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELKAKLLQEAK 320
            ....|.|   :.|.|..|.:..||..||..|.|...|..|.||  |.:|        ||..:...
  Fly   293 PLEDKMPAKSQQNPLTIDFLKKCLDKDPTKRWSCEKLTKHSYF--DDYI--------AKQRELEH 347

Human   321 VNSL 324
            ||||
  Fly   348 VNSL 351

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL3	XP_011541731.1	STKc_CDKL2_3	2..298	CDD:270836	134/300 (45%)
CG7236	NP_608950.3	STKc_CDKL1_4	48..335	CDD:270837	134/300 (45%)
		Pkinase	50..335	CDD:278497	134/298 (45%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D398098at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920