Protein Alignment CDKL3 and cdkl1

DIOPT Version :9

• Sequence 1: XP_011541731.1
• Gene: CDKL3 / 51265
• HGNCID: 15483
• Length: 619
• Species: Homo sapiens
• Sequence 2: XP_012825009.1
• Gene: cdkl1 / 100496578
• XenbaseID: XB-GENE-6051219
• Length: 352
• Species: Xenopus tropicalis
• Alignment Length: 354
• Identity: 155/354 - (43%)
• Similarity: 214/354 - (60%)
• Gaps: 18/354 - (5%)

Human     1 MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSV-NKIAMREIKFLKQFHHENLVN 64
            ||.||.:||:||||||.|.||::::||||||||.|.|..:..| .|||:|||:.|||..|.||||
 Frog     1 MEKYEKIGKIGEGSYGVVFKCRNRDTGQIVAIKKFLESEDDPVIKKIALREIRMLKQLKHPNLVN 65

Human    65 LIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNNIIHRDIKPE 129
            |:||||:|:|:|||||:.|||||.||..|..|:....::...:|.|:|:::.|.::.||||:|||
 Frog    66 LLEVFRRKRKLHLVFEYCDHTVLHELDKYPRGVPEHLVKSITWQTLQAVNFCHKHHCIHRDVKPE 130

Human   130 NILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGKYVYFGILSAFPRPV 194
            |||:::..:.|||||||||.|..|.|.|||||||||||||||::.||.||.            ||
 Frog   131 NILITRHSVIKLCDFGFARLLTGPSDYYTDYVATRWYRAPELLVGDTQYGP------------PV 183

Human   195 DIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLPQVQHPKN 259
            |:||:||:..|:.:|.|..|..||:|.|:.|....|:|....|.:||.:..|:||.:|..::.:.
 Frog   184 DVWAIGCVFAELLSGIPLWPGKSDVDQLYLIRKSQGDLIARHQQVFSTNQFFSGVSIPDPENMEP 248

Human   260 ARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTR-----DGFIEKFMPELKAKLLQEA 319
            ...::|.::.....::..||.:|||.|::...||.|.||..     ||..:......|...|...
 Frog   249 LELRFPNISSQALGLMKGCLHMDPAKRLACQQLLDHPYFDSIRDEGDGVTDSERLSRKQTRLHRK 313

Human   320 KVNSLIKPKESSKENELRKDERKTVYTNT 348
            .:..|....:.:..|.|...|.|..|.||
 Frog   314 YIPGLQHLPQLTSSNILPALESKKCYANT 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CDKL3	XP_011541731.1	STKc_CDKL2_3	2..298	CDD:270836	140/296 (47%)
cdkl1	XP_012825009.1	STKc_CDKL1_4	2..287	CDD:270837	140/296 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D245642at7742
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920