Protein Alignment ZNF219 and egrh-3

DIOPT Version :10

• Sequence 1: NP_057507.2
• Gene: ZNF219 / 51222
• HGNCID: 13011
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_001368224.1
• Gene: egrh-3 / 4363076
• WormBaseID: WBGene00044651
• Length: 320
• Species: Caenorhabditis elegans
• Alignment Length: 245
• Identity: 54/245 - (22%)
• Similarity: 83/245 - (33%)
• Gaps: 83/245 - (33%)

Human   447 GSLASLHPRPGEGPGHSASAAGAQARSTATQEENGLLVG-GTRPEGGRGATGKDCPF------CG 504
            |.|.:....|..|...::|::.....:|:|:::.|  .| |.||........|:.||      |.
 Worm    95 GLLGNNQQAPRGGTNGTSSSSTTATTTTSTKKKKG--QGPGRRPALDANGMPKERPFVCPRPDCQ 157

Human   505 KSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQSGSLKYHLQRHHR------------------- 550
            |.|....||:.|:|:|||:|.::|..|    .:|.|...||.:|.|
 Worm   158 KRFCRNDHLQRHMRIHTGQRLFQCRTC----LRSFSRSDHLAKHERTHSADKPYSCLTCARRFHK 218

Human   551 -----------------EQRSGAGPGPPPEPPPPSQRGSAPQSGAKPSPQPATWVEGASSPRPPS 598
                             :|:.|||            |......|...:..|...:...|...|.|
 Worm   219 HEEKKKHEEKCQHKVEDQQQGGAG------------RQQLNLMGNAHNMYPNQMILNGSMQSPNS 271

Human   599 S---------------GAGPGSRRKPASPGRTLRNGRGGEAEPLDLSLRA 633
            :               |||.|:.:..|.       |.|...:|..|.:|:
 Worm   272 NNLNMMIPATTFKLQGGAGGGASQASAP-------GGGSSQQPNPLEIRS 314

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF219	NP_057507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RPC10	53..>93	CDD:441599
		C2H2 Zn finger	59..79	CDD:275368
		zf-C2H2	85..107	CDD:395048
		C2H2 Zn finger	87..107	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..160
		C2H2 Zn finger	165..183	CDD:275368
		C2H2 Zn finger	191..207	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..275
		zf-C2H2	274..296	CDD:395048
		C2H2 Zn finger	276..296	CDD:275368
		zf-C2H2	302..324	CDD:395048
		C2H2 Zn finger	304..324	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..495		12/48 (25%)
		PTZ00449	<453..>612	CDD:185628	47/216 (22%)
		C2H2 Zn finger	500..520	CDD:275368	9/25 (36%)
		zf-C2H2	500..520	CDD:395048	9/25 (36%)
		zf-H2C2_2	512..537	CDD:463886	10/24 (42%)
		C2H2 Zn finger	528..548	CDD:275368	6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..648		24/143 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..722
egrh-3	NP_001368224.1	zf-C2H2	149..173	CDD:395048	8/23 (35%)
		C2H2 Zn finger	154..173	CDD:275368	7/18 (39%)
		zf-H2C2_2	165..190	CDD:463886	11/28 (39%)
		C2H2 Zn finger	181..201	CDD:275368	8/23 (35%)