Protein Alignment ZNF219 and ich

DIOPT Version :10

• Sequence 1: NP_057507.2
• Gene: ZNF219 / 51222
• HGNCID: 13011
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_649848.2
• Gene: ich / 41069
• FlyBaseID: FBgn0286204
• Length: 592
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 68/281 - (24%)
• Similarity: 97/281 - (34%)
• Gaps: 87/281 - (30%)

Human   355 EPLGPALL-LAPAPTPAERREPPSLL--GYLSL---RAGEGRPNGEGAEPGPGRSFG-GFR---- 408
            :.||..:| .:|.|..|......|||  ||:.|   |...|.|||..:..|.|.:.| |.:
  Fly   310 DSLGDFILPHSPLPMHASSSTLQSLLSHGYMPLLQNRLQNGPPNGNSSGGGGGANQGAGIKGDPQ 374

Human   409 -PLSSAL---PARARRHRAEEPEEEEEVVEAEEETWARGRSLG------SLASLHPRPG---EGP 460
             |.|::.   .|.|.......|.......:.........|.|.      :..:||.:.|   :..
  Fly   375 APTSTSYCNELAAATSSSCSPPGSVVSTTDNPNGLMINPRYLSNPTNNQATGNLHQQGGYSMQAS 439

Human   461 GHS--------------------ASAAGAQARSTA---------------------TQEENGLLV 484
            |.|                    ||..|::.|:.|                     .|::.|  .
  Fly   440 GLSLKDNGLCSPDLLGNYPHTTTASTTGSEMRTGAPKAKRSRSQKKSNQQQQQQQQQQQQQG--D 502

Human   485 GGTRPEGGR---------------GATGKD-----CPFCGKSFRSAHHLKVHLRVHTGERPYKCP 529
            ||.:|...:               |..||:     |..|.:.|.:..::|||||.||||:|::|.
  Fly   503 GGGQPTTPQMSAISPSGFSASDLSGLLGKEKPVHRCSICNRGFLNKSNIKVHLRTHTGEKPFRCD 567

Human   530 HCDYAGTQSGSLKYHLQRHHR 550
            .|..|..|...|..|.|.|.|
  Fly   568 VCAKAFRQKAHLLKHQQIHKR 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF219	NP_057507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RPC10	53..>93	CDD:441599
		C2H2 Zn finger	59..79	CDD:275368
		zf-C2H2	85..107	CDD:395048
		C2H2 Zn finger	87..107	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..160
		C2H2 Zn finger	165..183	CDD:275368
		C2H2 Zn finger	191..207	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..275
		zf-C2H2	274..296	CDD:395048
		C2H2 Zn finger	276..296	CDD:275368
		zf-C2H2	302..324	CDD:395048
		C2H2 Zn finger	304..324	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..495		32/187 (17%)
		PTZ00449	<453..>612	CDD:185628	39/162 (24%)
		C2H2 Zn finger	500..520	CDD:275368	8/19 (42%)
		zf-C2H2	500..520	CDD:395048	8/19 (42%)
		zf-H2C2_2	512..537	CDD:463886	13/24 (54%)
		C2H2 Zn finger	528..548	CDD:275368	7/19 (37%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..648		4/9 (44%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..722
ich	NP_649848.2	zf-C2H2	536..558	CDD:395048	8/21 (38%)
		C2H2 Zn finger	538..558	CDD:275368	8/19 (42%)
		zf-H2C2_2	550..575	CDD:463886	13/24 (54%)
		C2H2 Zn finger	566..586	CDD:275368	7/19 (37%)