Protein Alignment ZNF219 and CG10147

DIOPT Version :10

• Sequence 1: NP_057507.2
• Gene: ZNF219 / 51222
• HGNCID: 13011
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_648046.1
• Gene: CG10147 / 38733
• FlyBaseID: FBgn0035702
• Length: 448
• Species: Drosophila melanogaster
• Alignment Length: 336
• Identity: 74/336 - (22%)
• Similarity: 97/336 - (28%)
• Gaps: 117/336 - (34%)

Human    48 SESRAGER----RFPCPVCGKRFRFNSILALHLRAHPGAQAFQCPHCGHRAAQRALLR-SHLRTH 107
            :|.:|.|.    .:.|.:|...||....|.||.:.|.|...:   ||.....:.|..| .:||.|
  Fly   156 TEKKALEEPPLTTYKCDLCADEFREEKRLILHKKEHQGHMLY---HCTEPGCEEAFNRFENLRQH 217

Human   108 QPERPRSPAARLLLELE--ERALLREARL----------------------GRARSSG-GMQATP 147
            :.|. .....|.:.|.|  .|....:|.|                      ||...:| .:....
  Fly   218 ELEH-SEVGMRFVCEEEGCNRMYRHKASLKYHQSKAHDIGKPLKTHMCEFCGRVFKTGSALSQHR 281

Human   148 ATEG--LARPQA---PSSSA--------------------FRCPYCKGKFRTSAERERHL--HIL 185
            .|.|  |..|.|   |..|.                    |.||||..|..|..|...|:  |.|
  Fly   282 FTHGDQLVLPYACELPECSMRFYSTEKLKIHMMRHQGIKNFSCPYCGLKKTTKNELRLHINYHTL 346

Human   186 HRPWKCGLCSFGSSQEEELLHHSLTAHGAPERPLAATSAAPPPQPQPQPPPQPEPRSVPQPEPEP 250
            .|.|.|..|....:....|..|....|
  Fly   347 ERTWSCKDCPKVCNSSTSLKKHIRAIH-------------------------------------- 373

Human   251 EPEREATPTPAPAAPEEPPAPPEFRCQVCGQSFTQSWFLKGHMRKHKASFDHACPVCGRCFKEPW 315
            |..|                  ::.|..|.:.|..:...|.|...|....:..|.|||:.|.:|.
  Fly   374 EKAR------------------DYACSYCEKKFATTDTRKYHEMTHTGEKNFECHVCGKKFIQPS 420

Human   316 FLKNHMKVHAS 326
            .|:.|.|||.|
  Fly   421 ALRTHRKVHES 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF219	NP_057507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RPC10	53..>93	CDD:441599	12/43 (28%)
		C2H2 Zn finger	59..79	CDD:275368	7/19 (37%)
		zf-C2H2	85..107	CDD:395048	6/22 (27%)
		C2H2 Zn finger	87..107	CDD:275368	6/20 (30%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..160		7/28 (25%)
		C2H2 Zn finger	165..183	CDD:275368	8/19 (42%)
		C2H2 Zn finger	191..207	CDD:275368	3/15 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..275		2/59 (3%)
		zf-C2H2	274..296	CDD:395048	5/21 (24%)
		C2H2 Zn finger	276..296	CDD:275368	5/19 (26%)
		zf-C2H2	302..324	CDD:395048	9/21 (43%)
		C2H2 Zn finger	304..324	CDD:275368	9/19 (47%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..495
		PTZ00449	<453..>612	CDD:185628
		C2H2 Zn finger	500..520	CDD:275368
		zf-C2H2	500..520	CDD:395048
		zf-H2C2_2	512..537	CDD:463886
		C2H2 Zn finger	528..548	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..648
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..722
CG10147	NP_648046.1	zf-AD	7..80	CDD:214871
		C2H2 Zn finger	171..191	CDD:275368	7/19 (37%)
		C2H2 Zn finger	199..221	CDD:275368	6/21 (29%)
		SFP1	<228..284	CDD:227516	8/55 (15%)
		C2H2 Zn finger	230..253	CDD:275368	5/22 (23%)
		C2H2 Zn finger	264..284	CDD:275368	3/19 (16%)
		C2H2 Zn finger	294..316	CDD:275368	2/21 (10%)
		C2H2 Zn finger	324..344	CDD:275368	8/19 (42%)
		C2H2 Zn finger	352..373	CDD:275368	4/20 (20%)
		C2H2 Zn finger	381..401	CDD:275368	5/19 (26%)
		C2H2 Zn finger	409..429	CDD:275368	9/19 (47%)