Protein Alignment ZNF219 and lst-5

DIOPT Version :10

• Sequence 1: NP_057507.2
• Gene: ZNF219 / 51222
• HGNCID: 13011
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_872063.2
• Gene: lst-5 / 353399
• WormBaseID: WBGene00016890
• Length: 346
• Species: Caenorhabditis elegans
• Alignment Length: 238
• Identity: 45/238 - (18%)
• Similarity: 69/238 - (28%)
• Gaps: 89/238 - (37%)

Human    59 CPVCGKRFRFNSILALH-LRAHPG-AQAFQCPHCGHRAAQRALLRSHLRTHQPERPRSPAARLLL 121
            |.:|||.:...|:||.| |..|.. ....:||.|......:..|:.|::.|:.|..
 Worm   147 CDICGKIYSAVSVLAEHMLNEHNRYLDQIECPDCHEFFLTQTALQKHMKEHKREEK--------- 202

Human   122 ELEERALLREARLGRARSSGGMQATPATEGLARPQAPSSSAFRCPY--CKG-KFRTSAERERHLH 183
                                                      .|||  |:| |||.:.|...|:.
 Worm   203 ------------------------------------------HCPYKECRGIKFRFNRELNEHVR 225

Human   184 ILH--RPWKCGLCSFGSSQEEELLHHSLT-AHGAPERPLAATSAAPPPQPQPQ------------ 233
            :.|  :...|.:|:....|....:.|..| ..|:|...:..:|.......|.:
 Worm   226 LQHKSKELSCCVCNMVFRQLSAKIKHEKTHEKGSPISNILKSSKCSAVNRQVEKNQDWFRTRGSE 290

Human   234 ------------------PPPQPEPRSVPQPEPEPEPEREATP 258
                              ||...:.|.:..||.|..|..:..|
 Worm   291 RKAKCDEDLVKREPISDSPPSSAKRRKIYVPEFEAIPLTKKAP 333

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF219	NP_057507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RPC10	53..>93	CDD:441599	13/35 (37%)
		C2H2 Zn finger	59..79	CDD:275368	9/20 (45%)
		zf-C2H2	85..107	CDD:395048	5/21 (24%)
		C2H2 Zn finger	87..107	CDD:275368	5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..160		0/22 (0%)
		C2H2 Zn finger	165..183	CDD:275368	10/20 (50%)
		C2H2 Zn finger	191..207	CDD:275368	3/15 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..275		11/74 (15%)
		zf-C2H2	274..296	CDD:395048
		C2H2 Zn finger	276..296	CDD:275368
		zf-C2H2	302..324	CDD:395048
		C2H2 Zn finger	304..324	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..495
		PTZ00449	<453..>612	CDD:185628
		C2H2 Zn finger	500..520	CDD:275368
		zf-C2H2	500..520	CDD:395048
		zf-H2C2_2	512..537	CDD:463886
		C2H2 Zn finger	528..548	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..648
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..722
lst-5	NP_872063.2	C2H2 Zn finger	111..132	CDD:275368
		C2H2 Zn finger	147..168	CDD:275368	9/20 (45%)
		C2H2 Zn finger	177..197	CDD:275368	5/19 (26%)
		C2H2 Zn finger	208..227	CDD:275368	7/18 (39%)
		C2H2 Zn finger	235..255	CDD:275368	4/19 (21%)