Protein Alignment ZNF219 and CG4318

DIOPT Version :10

• Sequence 1: NP_057507.2
• Gene: ZNF219 / 51222
• HGNCID: 13011
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_572860.2
• Gene: CG4318 / 32266
• FlyBaseID: FBgn0030455
• Length: 236
• Species: Drosophila melanogaster
• Alignment Length: 141
• Identity: 34/141 - (24%)
• Similarity: 57/141 - (40%)
• Gaps: 30/141 - (21%)

Human   428 EEEEVVEAEEETWARGRSLGSLASLHP---------------RPGEG-----PGHSASAAGAQAR 472
            |::|:|.:|......|.:...:..:.|               .||:.     |..:::..|..::
  Fly    73 EQDEMVVSEMNYEEEGSNDSDVELIEPVDGSQEMETIDLTIDSPGDNVENMCPNSNSNGNGNVSQ 137

Human   473 STATQEENGLLVGGTRPEGGRGATGKDCPFCGKSFRSAHHLKVHLRVHTGERPYKCPHCDYAGTQ 537
            |:|.::....::..|.          .|..|||.|....|||.|:.||..|:||||..|..:..|
  Fly   138 SSAQKDTKKKMLKKTH----------KCNICGKYFMLPAHLKCHMWVHAREKPYKCLQCSQSYAQ 192

Human   538 SGSLKYHLQRH 548
            ...|:.|.:.|
  Fly   193 IRGLRRHERVH 203

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF219	NP_057507.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RPC10	53..>93	CDD:441599
		C2H2 Zn finger	59..79	CDD:275368
		zf-C2H2	85..107	CDD:395048
		C2H2 Zn finger	87..107	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	137..160
		C2H2 Zn finger	165..183	CDD:275368
		C2H2 Zn finger	191..207	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	215..275
		zf-C2H2	274..296	CDD:395048
		C2H2 Zn finger	276..296	CDD:275368
		zf-C2H2	302..324	CDD:395048
		C2H2 Zn finger	304..324	CDD:275368
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	384..495		13/86 (15%)
		PTZ00449	<453..>612	CDD:185628	29/116 (25%)
		C2H2 Zn finger	500..520	CDD:275368	9/19 (47%)
		zf-C2H2	500..520	CDD:395048	9/19 (47%)
		zf-H2C2_2	512..537	CDD:463886	12/24 (50%)
		C2H2 Zn finger	528..548	CDD:275368	5/19 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	542..648		2/7 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	668..722
CG4318	NP_572860.2	zf-AD	5..77	CDD:462262	1/3 (33%)
		C2H2 Zn finger	155..175	CDD:275368	9/19 (47%)
		C2H2 Zn finger	183..203	CDD:275368	5/19 (26%)
		C2H2 Zn finger	214..234	CDD:275368