Protein Alignment CPA4 and CG8560

DIOPT Version :10

• Sequence 1: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_648120.3
• Gene: CG8560 / 38830
• FlyBaseID: FBgn0035781
• Length: 418
• Species: Drosophila melanogaster
• Alignment Length: 422
• Identity: 142/422 - (33%)
• Similarity: 219/422 - (51%)
• Gaps: 28/422 - (6%)

Human    10 LIGSSICGQEKFFGDQVLRINVRNGDEISKLSQLVNSNNLKLNFWKSPSSFNRPVDVLVPSVSLQ 74
            |:.|.....|.:.|.::..||.||..|...|.:|  |.|...:|:..|.|.:....|:|.....:
  Fly    10 LLASVALAVENYDGYKIYDINARNAFEKQLLLRL--SGNEAYDFFDLPRSLDASSRVMVKPEDQE 72

Human    75 AFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHN-----EGQERSSNNFNYGAYHSLEAIYHEMD 134
            .|:..|...|:.|:|..|:....|..|.||.|:.     ...|||   .::.|:|....|...:|
  Fly    73 GFEHLLEKYGVNYSVINENFGESLRQERDENQNQRLMNLRSAERS---VSFKAFHRHAEINAYLD 134

Human   135 NIAADFPDLARRVKI---GHSFENRPMYVLKFSTGKG-VRRPAVWLNAGIHSREWISQATAIWTA 195
            .:||.:|.   ||.:   |.|:|||.:..:..:.|.| ..:..|:|:||||:||||:.|.|::..
  Fly   135 ELAAAYPS---RVSVQVAGKSYENRDIKTITITNGDGKTGKNVVFLDAGIHAREWIAHAGALYVI 196

Human   196 RKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCIGADPNRNWN 260
            .::|.::   .|.:.:|:..|..:|||.|||||.|:.|..|:||||| :...|:|.|.|.|||::
  Fly   197 HQLVENF---AANSELLKDFDWVILPVVNPDGYEYSHTTTRMWRKTR-KPISSACYGTDANRNFD 257

Human   261 ASFAGKGASDNPCSEVYHGPHANSEVEVKSVVD-FIQKHGNFKGFIDLHSYSQLLMYPYGYSVKK 324
            ..:...|||...||:.:.|..|.||.|.:.:.| .:...|..|.::.||||...|:||:|::...
  Fly   258 FHWGEVGASSYSCSDTFKGETAFSEPETQLIRDILLSLTGRGKFYLTLHSYGNYLLYPWGWTSAL 322

Human   325 APDAEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYDNGI---KFAFTFELRDT 386
            .....:.|:||:..|.|:.|.:||:|.||.:...:|.|:|.|.|:|:  |:   ..:.|.||...
  Fly   323 PSSWRDNDEVAQGGADAIKSATGTKYTVGSSTNVLYAAAGGSDDYAF--GVANFPVSITMELPAG 385

Human   387 GTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418
            || ||....:||.....|||:|:|.:.:.|.|
  Fly   386 GT-GFNPSTSQIEGFVSETWVGIKAMAQKVAD 416

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505	21/73 (29%)
		M14_CPA	118..419	CDD:349442	110/309 (36%)
CG8560	NP_648120.3	Propep_M14	27..99	CDD:460505	21/73 (29%)
		M14_CP_A-B_like	123..414	CDD:349433	107/300 (36%)