Protein Alignment CPA4 and CG14820

DIOPT Version :10

• Sequence 1: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_648060.1
• Gene: CG14820 / 38754
• FlyBaseID: FBgn0035718
• Length: 416
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 132/423 - (31%)
• Similarity: 221/423 - (52%)
• Gaps: 23/423 - (5%)

Human     4 ILFIGALIG-SSICGQEKFFGDQVLRINVRNGDEISKLSQL-VNSNNLKLNFWKSPSSFNRPVDV 66
            ||.:..|.| :....|.::...:|..:.:   |::.:...| ....:|||:.|:.........|:
  Fly     5 ILLVVGLFGLARSVEQVRYDNYKVYNVRI---DDLEQFKLLHTQERSLKLSSWREARHLGESSDI 66

Human    67 LVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYGAYHSLEAIYH 131
            ::|....:.|:|.|......|.:.|:::|..:|.:..:.:        ..:..:..:|:||.||.
  Fly    67 MLPPEYQKTFESLLTKHNFTYNLKIDNVQTHIDAQRPKQR--------ITSMEWTQFHTLEEIYA 123

Human   132 EMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWISQATAIWTAR 196
            .:|.|...:||:.....||:|:|.||:..:|.|..:|  .|||::.:.||:||||:.||..:...
  Fly   124 WLDVIEDRYPDIVTPFTIGNSYEGRPIRGVKISYKEG--NPAVFIESNIHAREWITSATITYFID 186

Human   197 KIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTR-SRNPGSSCIGADPNRNWN 260
            :::  ..|:||:..|.:.:|.:::||.|.||:.|:....|||||:| ..:|...|||.|.|||::
  Fly   187 ELL--VPRNPAVRDIAQNVDWYIIPVLNTDGFAYSHEVERLWRKSRLPSDPTGECIGTDLNRNFD 249

Human   261 ASFAGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK---HGNFKGFIDLHSYSQLLMYPYGYSV 322
            ..:...||..:|||::|.||...|:.|:..:..:|..   .|..|.:|.||||.|.::.|:|::.
  Fly   250 YLWMLTGAESDPCSQLYAGPSPESDPEISQLTAYINNSIPEGTIKIYISLHSYGQYVLSPWGHTA 314

Human   323 KKAPD-AEELDKVARLAAKALASVSGTEYQVGPTCTTVYPASGSSIDWAYD-NGIKFAFTFELRD 385
            .:.|: ..::..||:..:.||....||.:..|.:.||:|..|||..:|||. ..||..:|.||||
  Fly   315 LEFPEHYPQMMHVAKGFSDALYRRYGTVFTYGSSATTLYEVSGSGKEWAYAVKNIKIHYTIELRD 379

Human   386 TGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418
            .|..||:||...|||.|.|...|...::...|:
  Fly   380 KGELGFVLPPEDIIPVAREVTEGFVGMIAAARE 412

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505	15/74 (20%)
		M14_CPA	118..419	CDD:349442	111/307 (36%)
CG14820	NP_648060.1	Propep_M14	29..101	CDD:460505	15/74 (20%)
		M14_CP_A-B_like	115..406	CDD:349433	110/294 (37%)