Protein Alignment CPA4 and CG7025

DIOPT Version :10

• Sequence 1: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_609133.2
• Gene: CG7025 / 34042
• FlyBaseID: FBgn0031930
• Length: 429
• Species: Drosophila melanogaster
• Alignment Length: 375
• Identity: 134/375 - (35%)
• Similarity: 214/375 - (57%)
• Gaps: 28/375 - (7%)

Human    50 KLNFWKSPSSFNR-PVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQER 113
            :|:...||.:|.. ..::...:|:.:.|              |.::|.|:|:|:   ..|....|
  Fly    67 ELHLMLSPGAFGELETEIQKTNVTAELF--------------ISNVQELIDSEE---AANLKASR 114

Human   114 SSNNFNYGAYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNA 178
             ...|.:..|:||..||..:|:|.|.:|.:.....:|.|:|.|.:..:|.|...  ..|.|.:.:
  Fly   115 -DGTFGWTKYNSLAEIYAWLDDILAAYPTITESFIVGQSYEGRTIRGIKISYKS--NNPGVLIES 176

Human   179 GIHSREWISQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRS 243
            .||:||||:.|||.|...:.::  ..|..:..:.|..|.:::||.|.||:|||..::|:|||||.
  Fly   177 NIHAREWITSATATWLINEFLT--STDELVRDLAENHDWYIVPVLNVDGFVYTHEKDRMWRKTRQ 239

Human   244 RNPGSSCIGADPNRNWNASF-AGKGASDNPCSEVYHGPHANSEVEVKSVVDF-IQKHGNFKGFID 306
            .:..|||||||||||:::.: ..:|||.|||:|.|.||...||.|::::.:| |.........:.
  Fly   240 PSEISSCIGADPNRNYDSHWMENEGASSNPCAEDYGGPKPFSEPEIQAMSEFVISIKDKINVLLA 304

Human   307 LHSYSQLLMYPYGYSVKK-APDAEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDW 369
            .|||||||:.|||::.:: .|:.:::.:||:....|:.|:. ||.|:.|.....:|||||::|||
  Fly   305 FHSYSQLLLSPYGHTKEEFPPNFDDMMEVAKAYGDAVESLPYGTVYRYGSAAGILYPASGATIDW 369

Human   370 AY-DNGIKFAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418
            || :.|::.::|.|.||||.|||:||...|||.|||..:|:..::|..:|
  Fly   370 AYNEQGVEISYTIEFRDTGRYGFILPPVHIIPNAEEALIGIAALLEKCKD 419

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505	10/51 (20%)
		M14_CPA	118..419	CDD:349442	121/306 (40%)
CG7025	NP_609133.2	Propep_M14	35..105	CDD:460505	10/51 (20%)
		M14_CP_A-B_like	123..415	CDD:349433	118/295 (40%)