Protein Alignment CPA4 and CG18585

DIOPT Version :10

• Sequence 1: NP_057436.2
• Gene: CPA4 / 51200
• HGNCID: 15740
• Length: 421
• Species: Homo sapiens
• Sequence 2: NP_609132.1
• Gene: CG18585 / 34041
• FlyBaseID: FBgn0031929
• Length: 422
• Species: Drosophila melanogaster
• Alignment Length: 432
• Identity: 134/432 - (31%)
• Similarity: 232/432 - (53%)
• Gaps: 28/432 - (6%)

Human     1 MRWILFIGALIGSSICG------QEKFFGDQVLRINVRNGDE---ISKLSQLVNSNNLKLNFWKS 56
            ||.:..:..|:..:..|      :|::...:|.::.::|..:   |.|:.:|..    |.|.||.
  Fly     1 MRLLWLLATLVALTSAGILKDSPKERYDNFRVYKLTIQNKIQLAAIEKIGELTK----KYNIWKE 61

Human    57 PSSFNRPVDVLVPSVSLQAFKSFLRSQGLEYAVTIEDLQALLDNEDDEMQHNEGQERSSNNFNYG 121
            ....:|.:|::|....|..|:..|:...:...:.||::|..:|.|      .......|..|.:.
  Fly    62 YDERSRQIDIMVSPGELNHFQELLKFNNISSELMIENVQERIDEE------QVTPTADSATFGWT 120

Human   122 AYHSLEAIYHEMDNIAADFPDLARRVKIGHSFENRPMYVLKFSTGKGVRRPAVWLNAGIHSREWI 186
            .|:.||.|...:|.|...:|.:.....:|.|:|.|.:..:|.|...|  .|.:::.:.||:||||
  Fly   121 KYYELEEIEAWLDEILNAYPSVTEEFIVGKSYEGRTIRGIKISHKAG--NPGIFIESNIHAREWI 183

Human   187 SQATAIWTARKIVSDYQRDPAITSILEKMDIFLLPVANPDGYVYTQTQNRLWRKTRSRNPGSSCI 251
            :.|:|.|...::::  ..|..:.|:.:..|..::||.|.||:.|:..::|:|||||..:..::||
  Fly   184 TSASATWFINQLLT--SEDADVRSLADNYDWHIIPVFNVDGFEYSHKKDRMWRKTRQPHATNACI 246

Human   252 GADPNRNWNASF-AGKGASDNPCSEVYHGPHANSEVEVKSVVDFIQK-HGNFKGFIDLHSYSQLL 314
            |||.|||:::.: ...|||||||||.:.|.:..||.|.|::|:::.| ......:|..|||.|.|
  Fly   247 GADANRNFDSYWLQNNGASDNPCSETFAGDNPESEPEAKALVEYLTKIQDQISVYISFHSYGQYL 311

Human   315 MYPYGYSVKKAPD-AEELDKVARLAAKALASVS-GTEYQVGPTCTTVYPASGSSIDWAYDN-GIK 376
            :.|||::.::.|: ..::..:.:..|.|:.::. ||.||.|.|...:|.|:|:|:||.::. |.|
  Fly   312 LSPYGHTNEEFPENYNDILTIGKAFADAIEALPYGTVYQYGSTADVLYVATGTSVDWVFNELGKK 376

Human   377 FAFTFELRDTGTYGFLLPANQIIPTAEETWLGLKTIMEHVRD 418
            ..:|.|.||.|.|||:||..||||..||..:|:..::|..::
  Fly   377 IGYTIEYRDKGRYGFILPPVQIIPNCEELMVGMLALIEKTKE 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CPA4	NP_057436.2	Propep_M14	27..101	CDD:460505	18/76 (24%)
		M14_CPA	118..419	CDD:349442	108/306 (35%)
CG18585	NP_609132.1	Propep_M14	33..106	CDD:460505	18/76 (24%)
		M14_CP_A-B_like	122..412	CDD:349433	106/293 (36%)