Protein Alignment ZNF639 and YGR067C

DIOPT Version :10

• Sequence 1: NP_057415.1
• Gene: ZNF639 / 51193
• HGNCID: 30950
• Length: 485
• Species: Homo sapiens
• Sequence 2: NP_011581.4
• Gene: YGR067C / 852958
• SGDID: S000003299
• Length: 804
• Species: Saccharomyces cerevisiae
• Alignment Length: 212
• Identity: 50/212 - (23%)
• Similarity: 70/212 - (33%)
• Gaps: 55/212 - (25%)

Human   289 YWCEQCDVQFSSSSELYLHFQEHSCDEQYLCQFCEHETNDPEDLHSHVVNEHACKLIELSDKYNN 353
            |.|..|...||.|.....|.:.|:..:.:.||.|:|.....:.|..|:...|...|:
Yeast     8 YICSFCLKPFSRSEHKIRHERSHAGVKPFQCQVCKHSFVRRDLLQRHIRTVHRTFLL-------- 64

Human   354 GEHGQYSLLSKITFDKCK---NFFVCQVCGFRSR---LHTNVNRHVAIEHTKIFPHVCDD----- 407
                  |..:.:|.||..   :..|..|.....|   :.|.||..:.:....|..|....
Yeast    65 ------SSYASMTGDKADIPVSLGVGDVDSTSPRDIKMETLVNSMIKVNSGLINIHYHSSNVEKM 123

Human   408 -----C--GKGFSSMLE---YCKHLNSHLSEGIYLCQYCEYSTGQIEDLKIHLDFKHSADLPHKC 462
                 |  ||..||:.:   ..|.:.|.|...|.:....|||          |||..|.|:.
Yeast   124 DKQQRCVIGKESSSLKKGKSRFKQVKSRLESSISVKILQEYS----------LDFISSRDIL--- 175

Human   463 SDCLMRFGNERELISHL 479
              ...|.|     :|||
Yeast   176 --TFFRMG-----VSHL 185

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF639	NP_057415.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..20
		C2H2 Zn finger	235..255	CDD:275368
		C2H2 Zn finger	262..283	CDD:275368
		C2H2 Zn finger	291..307	CDD:275368	5/15 (33%)
		Interaction with CTNNA2. /evidence=ECO:0000269|PubMed:16182284	371..455		23/104 (22%)
		C2H2 Zn finger	376..397	CDD:275368	5/23 (22%)
		C2H2 Zn finger	405..425	CDD:275368	6/34 (18%)
		C2H2 Zn finger	433..454	CDD:275368	6/20 (30%)
		C2H2 Zn finger	462..482	CDD:275368	5/18 (28%)
YGR067C	NP_011581.4	C2H2 Zn finger	10..30	CDD:275368	6/19 (32%)
		zf-C2H2	36..57	CDD:395048	6/20 (30%)
		C2H2 Zn finger	38..57	CDD:275368	6/18 (33%)