Protein Alignment CRBN and Crbn

DIOPT Version :10

• Sequence 1: NP_057386.2
• Gene: CRBN / 51185
• HGNCID: 30185
• Length: 442
• Species: Homo sapiens
• Sequence 2: XP_063141931.1
• Gene: Crbn / 297498
• RGDID: 1310533
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 440
• Identity: 406/440 - (92%)
• Similarity: 419/440 - (95%)
• Gaps: 3/440 - (0%)

Human     6 DQQDAAHNMGNHLPLLPAESEEED---EMEVEDQDSKEAKKPNIINFDTSLPTSHTYLGADMEEF 67
            |.:...|:.....|...|:||:||   ||||||||||||:|||||||||||||||||||||||||
  Rat    94 DVEGLQHSCRARAPQWTADSEDEDDEIEMEVEDQDSKEARKPNIINFDTSLPTSHTYLGADMEEF 158

Human    68 HGRTLHDDDSCQVIPVLPQVMMILIPGQTLPLQLFHPQEVSMVRNLIQKDRTFAVLAYSNVQERE 132
            ||||||||||||||||||:|||||||||||||||.||||||||||||||||||||||||||||||
  Rat   159 HGRTLHDDDSCQVIPVLPEVMMILIPGQTLPLQLSHPQEVSMVRNLIQKDRTFAVLAYSNVQERE 223

Human   133 AQFGTTAEIYAYREEQDFGIEIVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAV 197
            ||||||||||||||||:||||:|||||||||||||||||||||||||||||||||||||||||||
  Rat   224 AQFGTTAEIYAYREEQEFGIEVVKVKAIGRQRFKVLELRTQSDGIQQAKVQILPECVLPSTMSAV 288

Human   198 QLESLNKCQIFPSKPVSREDQCSYKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLR 262
            |||||||||||||||:|.|||.|.|||||||||||||||||||||||||||||||||||||||||
  Rat   289 QLESLNKCQIFPSKPISWEDQYSCKWWQKYQKRKFHCANLTSWPRWLYSLYDAETLMDRIKKQLR 353

Human   263 EWDENLKDDSLPSNPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQ 327
            |||||||:||||:||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   354 EWDENLKEDSLPANPIDFSYRVAACLPIDDVLRIQLLKIGSAIQRLRCELDIMNKCTSLCCKQCQ 418

Human   328 ETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKACNLNLIGRPSTEHSWFPGYAWTVAQCK 392
            ||||||||||||||||||||||||||||||||||||||.||||||||||.||||||||||:||||
  Rat   419 ETEITTKNEIFSLSLCGPMAAYVNPHGYVHETLTVYKASNLNLIGRPSTVHSWFPGYAWTIAQCK 483

Human   393 ICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPDTEDEISPDKVILCL 442
            |||||||||||||||||||||||||||||||||||:||||||||||||||
  Rat   484 ICASHIGWKFTATKKDMSPQKFWGLTRSALLPTIPETEDEISPDKVILCL 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRBN	NP_057386.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..45		21/41 (51%)
		LON_substr_bdg	80..317	CDD:426647	226/236 (96%)
		CRBN_C_like	321..422	CDD:276940	97/100 (97%)
Crbn	XP_063141931.1	None