Protein Alignment DCXR and CG31546

DIOPT Version :10

• Sequence 1: NP_057370.1
• Gene: DCXR / 51181
• HGNCID: 18985
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_730973.1
• Gene: CG31546 / 40691
• FlyBaseID: FBgn0051546
• Length: 264
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 87/259 - (33%)
• Similarity: 125/259 - (48%)
• Gaps: 31/259 - (11%)

Human     3 LFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVREC--PGIEPVCVDLGDW- 64
            |..:|:.||:|||..|||....:.....||.:..|.|.:..|..:::.|  .|.||..: .||.
  Fly     9 LDFSGKVVLITGAASGIGAAAAEMFSKLGACLALVDREEEGLICVMKRCMKMGHEPYGI-AGDLL 72

Human    65 ----------EATERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVA 119
                      :.|||   ..|.:|:|||.|.:.............|....|.|:|:...:::::.
  Fly    73 KPPEIECIARKTTER---YEGKLDVLVNGAGIMPTGTLQSTELACFTHVMEANVRSGFYLTKLLL 134

Human   120 RGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT 184
            ..|:.  ..|:||||||.|..||..|...|..:|.|:|..|:.:||:|||..:|||||||.|:.|
  Fly   135 PQLLQ--CKGSIVNVSSVCGLRAFPNLVAYNMSKAAVDQFTRSLALDLGPQGVRVNAVNPGVIRT 197

Human   185 SMGQATWSD--------PHKAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
            ::.:|...|        .|..||.    .||:..|.:.|..||.||.|:.:...||.||||:||
  Fly   198 NLQKAGGMDEQSYAEFLEHSKKTH----ALGRIGEPKEVAAAICFLASELASFVTGVTLPVDGG 257

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCXR	NP_057370.1	XR_like_SDR_c	1..244	CDD:187609	87/259 (34%)
CG31546	NP_730973.1	Rossmann-fold NAD(P)(+)-binding proteins	11..261	CDD:473865	86/257 (33%)