Protein Alignment DCXR and CG3699

DIOPT Version :10

• Sequence 1: NP_057370.1
• Gene: DCXR / 51181
• HGNCID: 18985
• Length: 244
• Species: Homo sapiens
• Sequence 2: NP_569875.2
• Gene: CG3699 / 31046
• FlyBaseID: FBgn0040349
• Length: 251
• Species: Drosophila melanogaster
• Alignment Length: 244
• Identity: 85/244 - (34%)
• Similarity: 128/244 - (52%)
• Gaps: 10/244 - (4%)

Human     5 LAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPG--IEPVCVDL-GDWEA 66
            |:.:.|:||||..|||....|.|...||.:..|.|..|:|::..:...|  .|.|..|: .|.:|
  Fly     3 LSNKVVIVTGASSGIGAAIAQVLAREGATLALVGRNVANLEATKKSLKGTQAEIVVADVTKDADA 67

Human    67 -TERALGSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIARGVPGA 130
             .::.|...|.:|:|||||.:......:::..|.||.....|||.||.:::.|...|:.  ..||
  Fly    68 IVQQTLAKFGRIDVLVNNAGILGKGGLIDLDIEEFDAVLNTNLRGVILLTKAVLPHLLK--TKGA 130

Human   131 IVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMTSMGQATWSDPH 195
            :|||||....|.......|..:|.|||..||::|||:.|..:|||:|||..|:|::.:.......
  Fly   131 VVNVSSCAGIRPFAGALSYGVSKAALDQFTKIVALEMAPQGVRVNSVNPGFVVTNIHRNIGIVDE 195

Human   196 KAKTMLNRI----PLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
            :...||.|.    |:|:..:|..|..|:.||.|.::..|||:..|::||
  Fly   196 EYNGMLQRAINSHPMGRVGDVTEVAEAVAFLASSKASFTTGALFPIDGG 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DCXR	NP_057370.1	XR_like_SDR_c	1..244	CDD:187609	85/244 (35%)
CG3699	NP_569875.2	Rossmann-fold NAD(P)(+)-binding proteins	3..248	CDD:473865	85/244 (35%)