Protein Alignment HSD17B14 and CG17121

DIOPT Version :10

• Sequence 1: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_651114.1
• Gene: CG17121 / 42721
• FlyBaseID: FBgn0039043
• Length: 361
• Species: Drosophila melanogaster
• Alignment Length: 180
• Identity: 53/180 - (29%)
• Similarity: 89/180 - (49%)
• Gaps: 15/180 - (8%)

Human     8 AGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG---GRALEQELPGAV--FILCDVTQED 67
            :|||.:|||||.|:|..|.......|.::.:.|.:..|   ...|..::|..|  ....||:...
  Fly    91 SGKVALVTGGGSGLGREICLELARRGCKLAVVDVNSKGCYETVELLSKIPRCVAKAYKNDVSSPR 155

Human    68 DVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTL-TKLALPYL-- 129
            :::.:.::..:..|.:|.:||||...|....|...|.: ...:|:|| ||:|.: ||..||.:
  Fly   156 ELQLMAAKVEKELGPVDILVNNASLMPMTSTPSLKSDE-IDTILQLN-LGSYIMTTKEFLPKMIN 218

Human   130 RKSQGNVINISSLVGAIGQAQAVPYVATK----GAVTAMTKALALDESPY 175
            ||| |:::.:::|.|.:....|..|.|||    |.:.::...|.|.:..|
  Fly   219 RKS-GHLVAVNALAGLVPLPGAGIYTATKYGIEGFMESLRAELRLSDCDY 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	53/180 (29%)
CG17121	NP_651114.1	Rossmann-fold NAD(P)(+)-binding proteins	94..338	CDD:473865	51/177 (29%)