Protein Alignment HSD17B14 and CG7322

DIOPT Version :10

• Sequence 1: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_573333.2
• Gene: CG7322 / 32880
• FlyBaseID: FBgn0030968
• Length: 242
• Species: Drosophila melanogaster
• Alignment Length: 258
• Identity: 78/258 - (30%)
• Similarity: 126/258 - (48%)
• Gaps: 36/258 - (13%)

Human     5 TRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVV-ICDKDESGGRALEQELPGAVFILCDVTQEDD 68
            |..||||::|||.|.|||..:|:...::||.|: :..|.|.    |:|      .:..|......
  Fly     3 TDLAGKVILVTGAGAGIGQALVKQLASAGATVIAVARKPEQ----LQQ------LVAFDPVHIQP 57

Human    69 VK------TLVSETIRRFGRLDCVVNNAGHHPPPQRP-EETSAQGFRQLLELNLLGTYTLTKLAL 126
            ::      ..|.|.:.:...||.:|||||  ....:| ||.:.|.|....::|:...:.:|:..|
  Fly    58 LQLDLSGWQAVREGLAKVPLLDGLVNNAG--VAIIKPFEELTEQDFDTHFDVNIKAVFNVTQSLL 120

Human   127 PYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPL 191
            |.| |...:::|:||:..:........|.|||.|:.::||:|||:..|..:|||.::|..:.|.:
  Fly   121 PRL-KDGASIVNVSSIASSRSFGGHTAYSATKAALDSLTKSLALELGPRKIRVNSVNPTVVLTKM 184

Human   192 ----WEELAALMPDPRATIREGMLAQ-PLGRMGQPAE-VGAAAVFLASEANFCTGIELLVTGG 248
                |.:.|...|         :||. ||.|..:..| |.|....|:|:::|..|..:|:.||
  Fly   185 GADNWSDPAKSGP---------LLAHIPLNRFCEVQEVVDATGYLLSSKSSFVNGHHILLEGG 238

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	78/258 (30%)
CG7322	NP_573333.2	XR_like_SDR_c	1..242	CDD:187609	78/258 (30%)