Protein Alignment HSD17B14 and CG31937

DIOPT Version :10

• Sequence 1: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_608616.2
• Gene: CG31937 / 326177
• FlyBaseID: FBgn0031360
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 207
• Identity: 54/207 - (26%)
• Similarity: 88/207 - (42%)
• Gaps: 32/207 - (15%)

Human     9 GKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQ----------------ELPGAV 57
            |:||.:||...|||..:..:....|.::|:      ..|.|||                .....:
  Fly    46 GQVVWITGASSGIGRALALSLARHGVKLVL------SARRLEQLEQVQEECLAAARGLLATKDVL 104

Human    58 FILCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPE--ETSAQGFRQLLELNLLGTYT 120
            .|..|:...|:.||.::..:..|.|||.:|||||.   .||..  |...:..|:|.||::.....
  Fly   105 VIQMDMLDLDEHKTHLNTVLNHFHRLDVLVNNAGR---SQRASWTEVEIEVDRELFELDVFAVVH 166

Human   121 LTKLALPYL---RKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCI 182
            |::|.:.|.   ...:|::...||:.|......:..|.|.|.|:.|...:|.::...  :.|:..
  Fly   167 LSRLVVRYFVEQNGGRGHIAATSSIAGFSPVPFSPTYCAAKHALNAYLLSLKVEMRK--LDVSLF 229

Human   183 SPGNIWTPLWEE 194
            :||.|.|...:|
  Fly   230 APGPIATDFLQE 241

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	54/207 (26%)
CG31937	NP_608616.2	Rossmann-fold NAD(P)(+)-binding proteins	44..293	CDD:473865	54/207 (26%)