Protein Alignment HSD17B14 and CG3603

DIOPT Version :10

• Sequence 1: NP_057330.2
• Gene: HSD17B14 / 51171
• HGNCID: 23238
• Length: 270
• Species: Homo sapiens
• Sequence 2: NP_570046.1
• Gene: CG3603 / 31289
• FlyBaseID: FBgn0029648
• Length: 249
• Species: Drosophila melanogaster
• Alignment Length: 259
• Identity: 82/259 - (31%)
• Similarity: 137/259 - (52%)
• Gaps: 23/259 - (8%)

Human     1 MATGTRYAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESGGRALEQELPG--AVFILCDV 63
            |:.|. .||||.:|||.|.|||....|.....||:|:..|::....:...|||..  :..:..||
  Fly     1 MSVGV-LAGKVALVTGAGSGIGRATCRLLARDGAKVIAVDRNLKAAQETVQELGSERSAALEVDV 64

Human    64 TQEDDVKTLVSETIRRFGRL-DCVVNNAGHHPPP---QRPEETSAQGFRQLLELNLLGTYTLTKL 124
            :....|:..|:|.:::|.:. ..|||:||.....   :.||    :.:..:..:||.||:.:|:.
  Fly    65 SSAQSVQFSVAEALKKFQQAPTIVVNSAGITRDGYLLKMPE----RDYDDVYGVNLKGTFLVTQA 125

Human   125 ---ALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGN 186
               |:...:...|.::|:||:|..:.......|.|||..|.:.|:..:.:...:|:|||||.||.
  Fly   126 YAKAMIEQKLENGTIVNLSSIVAKMNNVGQANYAATKAGVISFTEVASKEFGKFGIRVNCILPGY 190

Human   187 IWTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLAS-EANFCTGIELLVTGG 248
            |.||    :.|::||   ::::.::.: ||||:|||.|:.....|||| ::::..|..:.||||
  Fly   191 IDTP----MVAVVPD---SVKQEVVQRCPLGRLGQPEEIAEVIAFLASPQSSYVNGAAIEVTGG 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B14	NP_057330.2	RDH_SDR_c	1..256	CDD:187638	82/259 (32%)
CG3603	NP_570046.1	BKR_SDR_c	9..248	CDD:187594	78/250 (31%)