Protein Alignment HSD17B11 and CG13833

DIOPT Version :10

• Sequence 1: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_651111.1
• Gene: CG13833 / 42718
• FlyBaseID: FBgn0039040
• Length: 321
• Species: Drosophila melanogaster
• Alignment Length: 293
• Identity: 88/293 - (30%)
• Similarity: 148/293 - (50%)
• Gaps: 13/293 - (4%)

Human     4 LLDILLLLPLLIVCSL--ESFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLW 66
            |:.:..:.||||:.:|  ....||......||:.||:.::||||||:||..:.|.||....:.:.
  Fly    18 LIGLAAITPLLILVALLGRLIAKLCWCSAPKSIAGEVAVVTGAGHGLGRAISLELAKKGCHIAVV 82

Human    67 DINKHGLEETAAKCKGL-GAKVHTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLF 130
            |||..|.|:|..:.:.: ..:...:..:.:|.:|:.....||..|:|.|::|||||||:...::|
  Fly    83 DINVSGAEDTVKQIQDIYKVRAKAYKANVTNYDDLVELNSKVVEEMGPVTVLVNNAGVMMHRNMF 147

Human   131 ATQDPQIEKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGF 195
            ......::....||:.:||||...|||.|.:...|.|||::|.||...:|:...|.::|..|:..
  Fly   148 NPDPADVQLMINVNLTSHFWTKLVFLPKMKELRKGFIVTISSLAGVFPLPYSATYTTTKSGALAH 212

Human   196 HKTLTDELAALQITGVKTTCLCPNFVNTGF-IKNPSTSLG-----PTLEPEEVVNRLMHGILTEQ 254
            .:||..||.......:..|.:.|:|:.|.. :...:.::|     |....|||..|::.|::..:
  Fly   213 MRTLRMELDLENQKDIHVTTVLPSFLRTNSDVTQLTHTIGFGDVYPLFTGEEVAQRIVAGMVRGE 277

Human   255 KMIFIPSSIAFLTTLERILP----ERFLAVLKR 283
            ..|.:|.....|..:..|||    :|.:.:..|
  Fly   278 AEITVPGMACLLYRVILILPADWQDRIILLFSR 310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	74/249 (30%)
CG13833	NP_651111.1	YqjQ	49..305	CDD:440069	78/255 (31%)