Protein Alignment HSD17B11 and Adh

DIOPT Version :10

• Sequence 1: NP_057329.3
• Gene: HSD17B11 / 51170
• HGNCID: 22960
• Length: 300
• Species: Homo sapiens
• Sequence 2: NP_001027266.1
• Gene: Adh / 3771877
• FlyBaseID: FBgn0000055
• Length: 256
• Species: Drosophila melanogaster
• Alignment Length: 222
• Identity: 62/222 - (27%)
• Similarity: 92/222 - (41%)
• Gaps: 31/222 - (13%)

Human    38 IVLITGAGHGIGRLTAYEFAK--LKSKLVLWDINKHGLEETA--AKCKGLGAKVHTFVVDCSNRE 98
            ::.:.|.| |||..|:.|..|  ||:.::|     ..:|..|  |:.|.:..||...........
  Fly    10 VIFVAGLG-GIGLDTSKELLKRDLKNLVIL-----DRIENPAAIAELKAINPKVTVTFYPYDVTV 68

Human    99 DIYSSAKKVK---AEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLAHFWTTKAFLPAMT 160
            .|..:.|.:|   |::..|.:|:|.||::        .|.|||:|..||......||.|.|....
  Fly    69 PIAETTKLLKTIFAQLKTVDVLINGAGIL--------DDHQIERTIAVNYTGLVNTTTAILDFWD 125

Human   161 KNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELAAL-QITGVKTTCLCPNFV 221
            |...|.   |..:.|..|..::..:..|..:|.|.|.|    |..||.| .||||....:.|...
  Fly   126 KRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNF----TSSLAKLAPITGVTAYTVNPGIT 186

Human   222 NTGFIKNPSTSLGPTLEPEEVVNRLMH 248
            .|..:...::.|  .:||:.....|.|
  Fly   187 RTTLVHTFNSWL--DVEPQVAEKLLAH 211

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
HSD17B11	NP_057329.3	17beta-HSDXI-like_SDR_c	38..277	CDD:187598	62/222 (28%)
Adh	NP_001027266.1	ADH_SDR_c_like	8..247	CDD:187584	62/222 (28%)