Protein Alignment SDF4 and scf

DIOPT Version :10

• Sequence 1: XP_047278067.1
• Gene: SDF4 / 51150
• HGNCID: 24188
• Length: 362
• Species: Homo sapiens
• Sequence 2: NP_477392.1
• Gene: scf / 38145
• FlyBaseID: FBgn0025682
• Length: 329
• Species: Drosophila melanogaster
• Alignment Length: 351
• Identity: 102/351 - (29%)
• Similarity: 168/351 - (47%)
• Gaps: 42/351 - (11%)

Human    25 LLGAVLLMDASARPANHSSTRERVA-NREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLG 88
            :|..|:.:.|....|:.||..|.:. |..|::.|.|.|.:|      |..|..|..|.|||.|..
  Fly     8 MLLLVVALTAVISGASASSIPEELPHNPLEHDPLHPRHFDG------GEHNAQFDHEAFLGPDES 66

Human    89 GFDEDAEPRRSRRKLMVIFSKVDVNTDRKISAKEMQRWIMEKTAEHFQEAMEES-KTHFRAVDPD 152
            ...:...|..|||:|.||..::|.|.|..::..|::.||......:.:|.:... |.|    :||
  Fly    67 KKFDSLTPEESRRRLGVIVDRIDENKDGSVTLAELKNWIAYTQRRYIEEDVGRVWKQH----NPD 127

Human   153 GDGHVSWDEYKVKFLASKGHSEKEVADAIRLNEELKVDEETQE--------VLENLKDRWYQADS 209
            .:..:|||.|              :.......::|..||:.||        :|:..:.||..||.
  Fly   128 NNETISWDSY--------------MQTVYGFMDDLSPDEKEQEENGVSYKSLLKRDRYRWSVADQ 178

Human   210 PPADLLLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQG-QD 273
             ..|..||::||.:|||||....|...:::|.:.|||:|.|.::||.|:|    |.:....| :|
  Fly   179 -DLDDNLTKDEFTAFLHPEDHPSMKGVVLRETITDLDKDHDGKISVDEYI----GDMYRSTGAED 238

Human   274 IDDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHLEPEE 338
            .:..||.:.::.|....|.:.||.:..||::.::.|.:..::..|||.::..||.:.:..|..||
  Fly   239 EEPEWVANEREAFSTHRDLDKDGYLNEEEVKQWIAPHDFDHSEAEAKHLLFEADADHDDKLTKEE 303

Human   339 VLKYSEFFTGSKLVDYARSV--HEEF 362
            :|...:.|.||:..|:..::  |:||
  Fly   304 ILDKYDVFVGSQATDFGEALARHDEF 329

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SDF4	XP_047278067.1	EFh_CREC_cab45	67..347	CDD:320023	82/289 (28%)
		EF-hand motif	67..95	CDD:320023	8/27 (30%)
		EF-hand motif	102..131	CDD:320023	9/28 (32%)
		EF-hand motif	141..170	CDD:320023	8/29 (28%)
		EF-hand motif	199..229	CDD:320023	13/29 (45%)
		EF-hand motif	237..266	CDD:320023	11/28 (39%)
		EF-hand motif	282..311	CDD:320023	7/28 (25%)
		EF-hand motif	318..347	CDD:320023	9/28 (32%)
scf	NP_477392.1	EFh_CREC_Calumenin_like	45..313	CDD:320024	85/296 (29%)
		EF-hand motif	45..74	CDD:320024	10/34 (29%)
		EF-hand motif	80..109	CDD:320024	9/28 (32%)
		EF-hand motif	116..145	CDD:320024	8/46 (17%)
		EF-hand motif	168..197	CDD:320024	13/29 (45%)
		EF-hand motif	205..234	CDD:320024	11/32 (34%)
		EF-hand motif	247..276	CDD:320024	7/28 (25%)
		EF-hand motif	283..313	CDD:320024	10/29 (34%)