Protein Alignment CHCHD2 and MIX17

DIOPT Version :10

• Sequence 1: NP_001307256.1
• Gene: CHCHD2 / 51142
• HGNCID: 21645
• Length: 168
• Species: Homo sapiens
• Sequence 2: NP_013715.1
• Gene: MIX17 / 855014
• SGDID: S000004604
• Length: 156
• Species: Saccharomyces cerevisiae
• Alignment Length: 156
• Identity: 65/156 - (41%)
• Similarity: 85/156 - (54%)
• Gaps: 19/156 - (12%)

Human     3 RGSRSRTSRMAPPASRAPQMRAAP-RPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAGV 66
            |||....||..|..:|:....||| .|....||.|.:.|.|.|   |..||||:.||||:|||||
Yeast     5 RGSSRPISRSRPTQTRSASTMAAPVHPQQQQQPNAYSHPPAAG---AQTRQPGMFAQMASTAAGV 66

Human    67 AVGSAVGHTLGHAITGGFSG-GSNAEPARPDITYQEPQG-------TQPAQQ-QQPCLYEIKQFL 122
            ||||.:|||||..|||.||| ||::.|..     |:.|.       ||..|| .:.|..:.:.|.
Yeast    67 AVGSTIGHTLGAGITGMFSGSGSDSAPVE-----QQQQNMANTSGQTQTDQQLGRTCEIDARNFT 126

Human   123 ECA-QNQGDIKLCEGFNEVLKQCRLA 147
            .|. :|.|:.::|:.:.:.||.|:.|
Yeast   127 RCLDENNGNFQICDYYLQQLKACQEA 152

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CHCHD2	NP_001307256.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..50		18/47 (38%)
		COG3416	<4..>93	CDD:442642	47/90 (52%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	77..111		16/42 (38%)
		Cx9C motif 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	114..124		2/9 (22%)
		Cx9C motif 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU01150	134..144		3/9 (33%)
MIX17	NP_013715.1	COG3416	<12..>87	CDD:442642	42/77 (55%)
		CHCH	118..152	CDD:429096	9/33 (27%)