DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CHCHD2 and CG31008

DIOPT Version :9

Sequence 1:	NP_001307256.1	Gene:	CHCHD2 / 51142	HGNCID:	21645	Length:	168	Species:	Homo sapiens
Sequence 2:	NP_733411.1	Gene:	CG31008 / 318554	FlyBaseID:	FBgn0051008	Length:	114	Species:	Drosophila melanogaster

Alignment Length:	144	Identity:	40/144 - (27%)
Similarity:	63/144 - (43%)	Gaps:	36/144 - (25%)

- Green bases have known domain annotations that are detailed below.

Human     1 MPRGSRSRTSRMAPPASRAPQMRAAPRPAPVAQPPAAAPPSAVGSSAAAPRQPGLMAQMATTAAG 65
            |||..||                |:.:.......||..|  .|.:|..      :..:.|..|.|
  Fly     1 MPRKQRS----------------ASVKAGSTNYMPAVVP--TVTNSEM------VFKEAAAHAVG 41

Human    66 VAVGSAVGHTLGHAITGGFSGGSNAEPARPDITYQEPQGTQPAQQQQPCLYEIKQFLECAQNQGD 130
            ||.||.|||.:|..|||.|. ..:.:|...|:.           ::.||..|:|:||:|.::..|
  Fly    42 VAAGSVVGHAIGSGITGLFR-RRDQQPHHSDLV-----------EEGPCAKEMKEFLKCTEDNDD 94

Human   131 IKLCEGFNEVLKQC 144
            :.:|:.||:.:::|
  Fly    95 LSVCKEFNDAVRRC 108

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CHCHD2	NP_001307256.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..50		11/48 (23%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	77..111		7/33 (21%)
		CHCH	114..147	CDD:369061	11/31 (35%)
		Cx9C motif 1. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	114..124		5/9 (56%)
		Cx9C motif 2. /evidence=ECO:0000255\|PROSITE-ProRule:PRU01150	134..144		3/9 (33%)
CG31008	NP_733411.1	CHCH	78..111	CDD:284221	11/31 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12296
eggNOG	1	0.900	-	-		E1_KOG4090
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR13523
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.870