DRSC/TRiP Functional Genomics Resources

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Protein Alignment PHF11 and Phf7

DIOPT Version :10

Sequence 1:NP_001035533.1 Gene:PHF11 / 51131 HGNCID:17024 Length:331 Species:Homo sapiens
Sequence 2:NP_608374.1 Gene:Phf7 / 33015 FlyBaseID:FBgn0031091 Length:520 Species:Drosophila melanogaster


Alignment Length:415 Identity:89/415 - (21%)
Similarity:133/415 - (32%) Gaps:153/415 - (36%)


- Green bases have known domain annotations that are detailed below.


Human    45 CALCPKDVEYNVLYFAQ---SENIAAHENCLLYSSGLVECEDQDPLNPDRSFDVESVKKEIQRGR 106
            |.||... |.:.|.|..   ..|:..|.|||..||.|:: ..:..|: ..:|..|.::.|:.|.|
  Fly     5 CVLCLSG-ERDELIFGTVHVEGNMMVHRNCLYLSSNLIQ-RGEKKLS-IMNFLKEDIEAEVNRCR 66

Human   107 KLKCKFCHKRGATVGCDLKNCNKNYHFFCAKKDDAVPQSDGVRGIYKLLCQQHAQFP-------- 163
            .|||.:|.:.||.:.|....|.:.:|..|...:.|..|   ....|...|.||...|        
  Fly    67 LLKCCYCRRLGANIWCCKSGCRRTFHTKCGVDNLAQNQ---FCDTYNSFCHQHVLVPRNRPVFKN 128

Human   164 ----------IIAQSAKFSGV--------------KRKRGRKKPLSGNHVQPPETMKCN------ 198
                      ::|:..:||.|              :|...|....||...:.|   .||      
  Fly   129 DEECLLCAEDVVAKGERFSVVTCLYAPCCRNGWFHRRCLQRYANSSGYFFKCP---LCNNTDVFR 190

Human   199 ---------------------TFIRQVKEE-----------HGRHTDATVKVPFLKKCKEAGLLN 231
                                 .|..|.:.:           .|| .|.:..:.:...| .|...:
  Fly   191 RVAYMGIAVLDQDASWETEPDAFAGQYRRDVNCTAALCVAVSGR-ADTSAMLLYCTSC-GANPSH 253

Human   232 YL-----LEEILDKVHSI--PEKL------------MD-----------------ETTSESDYEE 260
            ||     |:..:.||.|.  ||.:            ||                 |..|.|.:::
  Fly   254 YLCTLKTLQNYVCKVCSAVSPEAVPVAESDSDDAGSMDDSAEAPRPGHLNGDQIQEKLSPSHWDD 318

Human   261 IGSALFDCRLFEDTFVNFQAAIEKKIHASQQRWQQLKEE-------IELLQD------------- 305
            .||:       :|..| ||.|.:.|:   |.|...|.::       ...|.|             
  Fly   319 FGSS-------DDDAV-FQRAFDTKV---QSRVVTLSDDQPSTSAGARALADRGTRTFESQGTQT 372

Human   306 --LKQTLCSFQENRDLMSSSTSISS 328
              |...:.||:......:||||.|:
  Fly   373 TFLSSVVTSFRSATATATSSTSTST 397

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PHF11NP_001035533.1 ePHD_PHF11 45..159 CDD:277182 34/116 (29%)
Phf7NP_608374.1 ePHD_PHF7_G2E3_like 5..116 CDD:277139 34/116 (29%)
RING_Ubox 129..183 CDD:473075 9/56 (16%)

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