Protein Alignment ZDHHC9 and app

DIOPT Version :9

• Sequence 1: NP_001008223.1
• Gene: ZDHHC9 / 51114
• HGNCID: 18475
• Length: 364
• Species: Homo sapiens
• Sequence 2: NP_648561.2
• Gene: app / 39399
• FlyBaseID: FBgn0260941
• Length: 755
• Species: Drosophila melanogaster
• Alignment Length: 344
• Identity: 184/344 - (53%)
• Similarity: 239/344 - (69%)
• Gaps: 14/344 - (4%)

Human     2 SVMVVRKKVTRKWEKLPGRNTFCCDGRVMMARQKGIFYLTLFLILGTCTLFFAFECRYLAVQLSP 66
            |.|...::||||||...|||.|.|||.:|.|...|:||||..||.||..|||||:|.:||..::|
  Fly    10 SNMAPNQRVTRKWELFAGRNKFYCDGLLMSAPHTGVFYLTCILITGTSALFFAFDCPFLADSINP 74

Human    67 AIPVFAAMLFLFSMATLLRTSFSDPGVIPRALPDEAAFIEMEIEATNGAVPQGQRPPPRIKNFQI 131
            |||:..|:|:.|:|::||||:|:||||||||..||||:||.:||..|.......|||||.|...:
  Fly    75 AIPIVGAVLYFFTMSSLLRTTFTDPGVIPRASNDEAAYIEKQIEVPNSLNSPTYRPPPRTKEVLV 139

Human   132 NNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGKRNYRYFYLFILSLSLLTI 196
            ..|.||||||:||||||||||||||:|||||:|||||||||||||||||||:||||::||:.|.:
  Fly   140 KGQTVKLKYCFTCKIFRPPRASHCSLCDNCVDRFDHHCPWVGNCVGKRNYRFFYLFLVSLAFLAV 204

Human   197 YVFAFNIVYVAL---KSLKIGFLETLKETPGTVLEVLICFFTLWSVVGLTGFHTFLVALNQTTNE 258
            ::|:.::.::.|   |..::  ...:|..|.||:.|.||||::|||:||.||||:|...:|||||
  Fly   205 FIFSCSVTHLVLLMKKEHEV--FNVIKAAPFTVIVVFICFFSIWSVIGLAGFHTYLTTSDQTTNE 267

Human   259 DIKGSWTGKN--RVQNPYSHGNIVKNCCEVLCGPLPPSVLDRRGILPLE--ESGSRPPSTQETSS 319
            |:|||::.|.  |.|||||.|||..|||.:||||:.||::|||||...|  :......|.:...|
  Fly   268 DLKGSFSSKGGPRTQNPYSRGNICLNCCHILCGPMTPSLIDRRGIATDEFIQQMQHQSSPRHALS 332

Human   320 SLLPQSPAPTEHLNSNEMP 338
            .:|..|     |:.:...|
  Fly   333 DVLSAS-----HMVTTSQP 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC9	NP_001008223.1	DHHC	138..261	CDD:396215	77/125 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	303..364		7/38 (18%)
app	NP_648561.2	zf-DHHC	146..270	CDD:279823	77/125 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	206	1.000	Domainoid score	I2911
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1264614at2759
OrthoFinder	1	1.000	-	-		FOG0000285
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100625
Panther	1	1.100	-	-	O	PTHR22883
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R405
SonicParanoid	1	1.000	-	-		X394
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	10	9.810