DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC9 and CG4483

DIOPT Version :9

Sequence 1:	NP_001008223.1	Gene:	ZDHHC9 / 51114	HGNCID:	18475	Length:	364	Species:	Homo sapiens
Sequence 2:	NP_648294.1	Gene:	CG4483 / 39057	FlyBaseID:	FBgn0035970	Length:	435	Species:	Drosophila melanogaster

Alignment Length:	188	Identity:	52/188 - (27%)
Similarity:	79/188 - (42%)	Gaps:	42/188 - (22%)

- Green bases have known domain annotations that are detailed below.

Human   114 GAVPQGQRPPPRIKNFQINNQIVKLKYCYTCKIFRPPRASHCSICDNCVERFDHHCPWVGNCVGK 178
            |.||....|       |:....:.|::|..|..::.||:.||..|:.||.:.||||||:..|||.
  Fly    74 GFVPLKWHP-------QLTKDKMFLQFCTRCNGYKAPRSHHCRRCNRCVMKMDHHCPWINTCVGW 131

Human   179 RN---YRYFYLFILSLSLLTIYVFAFNIVYVALKSLKIGF-----LETLKETPGTVLEVLICFFT 235
            .|   :.||.||.:|.|:....:    ||...::.:|..:     |..:.....|...:|.|.|:
  Fly   132 SNQDSFVYFLLFFMSGSIHGGII----IVSAVIRGIKKRWLIRYGLRHMATVHLTQTNLLACVFS 192

Human   236 LWSVVGLTGFHTFLVAL------------NQTTNEDIKGSWTGKNRV--QNPYSHGNI 279
            |..::|     |.|.::            |||..|    :|..|...  :|.|....|
  Fly   193 LGVIMG-----TVLASIKLLYMQMKSILKNQTEIE----NWIVKKAAFRRNAYPRKGI 241

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC9	NP_001008223.1	DHHC	138..261	CDD:396215	42/142 (30%)
ZDHHC9	NP_001008223.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	303..364
CG4483	NP_648294.1	zf-DHHC	88..224	CDD:279823	42/148 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810