Protein Alignment METTL9 and CG5339

DIOPT Version :10

• Sequence 1: NP_057109.3
• Gene: METTL9 / 51108
• HGNCID: 24586
• Length: 318
• Species: Homo sapiens
• Sequence 2: NP_611846.1
• Gene: CG5339 / 37794
• FlyBaseID: FBgn0034925
• Length: 305
• Species: Drosophila melanogaster
• Alignment Length: 281
• Identity: 101/281 - (35%)
• Similarity: 153/281 - (54%)
• Gaps: 25/281 - (8%)

Human    52 ENHQWYVCNREKLCESLQAVFVQSYLDQGTQIFLNNSIEKSGWLFIQLYHSFVSSVFSLFMSRTS 116
            :..:||..|.| |....|:.||....|..|..:|..:...|..::..|:|:...|:...||::|.
  Fly    28 DTRKWYCLNHE-LPPRFQSKFVPLEPDATTVSWLERTKALSANIWTHLWHALARSILQFFMTQTD 91

Human   117 INGLLGRGSMFVFSPDQFQRLLKIN-----PDWKTHRLLDLGAGDGEVTKIMSPHFEE------- 169
            |||.|.|||||:.|.:||::||...     ...:...|||:||||||::..::....|
  Fly    92 INGFLKRGSMFILSEEQFRKLLVAGGFQPASGQEPVTLLDIGAGDGEISLRVANTVSELSGSAGL 156

Human   170 -IYATELSETMIWQLQKKKYRVL-GINEWQNTGFQYDVISCLNLLDRCDQPLTLLKDIRSVLEPT 232
             ::|||.|.||..:|:|..:.|: .|:..||    .::|.|||:||||.....||:||...|.|
  Fly   157 RVFATEASWTMRDRLKKLNFNVITEIDGLQN----LELILCLNVLDRCFDSFKLLEDIHLALAP- 216

Human   233 RGRVILALVLPFHPYVE-NVGGKWEKPSEILEIKGQ--NWEEQVNSLPEVFRKAGFVIEAFTRLP 294
            .||.::|||||:..||| |......:|  :||..|:  ::||:.....|:....|:.:||:|:.|
  Fly   217 NGRAVVALVLPYMHYVETNTSHLPLRP--LLENNGRQASFEEEAARFMELLENCGYRVEAWTKAP 279

Human   295 YLCEGDMYNDYYVLDDAVFVL 315
            ||||||::..:|.|.|.:.|:
  Fly   280 YLCEGDLHQSFYWLIDLIVVI 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
METTL9	NP_057109.3	DREV	56..317	CDD:253097	101/277 (36%)
CG5339	NP_611846.1	AdoMet_MTases	32..302	CDD:473071	101/277 (36%)