Protein Alignment MECR and CG16935

DIOPT Version :10

• Sequence 1: XP_011539841.1
• Gene: MECR / 51102
• HGNCID: 19691
• Length: 459
• Species: Homo sapiens
• Sequence 2: NP_610914.2
• Gene: CG16935 / 36540
• FlyBaseID: FBgn0033883
• Length: 357
• Species: Drosophila melanogaster
• Alignment Length: 423
• Identity: 157/423 - (37%)
• Similarity: 210/423 - (49%)
• Gaps: 98/423 - (23%)

Human    44 RALVYGHHGDPAKVVEGITRELFQRFPWIFLQLITAVISSASTVLKNLELAAVRGSDVRVKMLAA 108
            ::|.|..||:|.:|                |||:..            :|...:.:.|.||:|||
  Fly    24 KSLKYTQHGEPQEV----------------LQLVED------------KLPDPKDNQVLVKILAA 60

Human   109 PINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPANAGLGTWRTEAVFS 173
            ||||:|||.|||.|...|:.|||||||.||:|:.||..|.|.:.|..|||..:|||||.|.||:.
  Fly    61 PINPADINTIQGKYPVKPKFPAVGGNECVAEVICVGDKVKGFEAGQHVIPLASGLGTWTTHAVYK 125

Human   174 EEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLR 238
            |:.|:.|...:.|..|||..|||.||||||.||.||.|||:||||.:||.|||||.|:..|.|:.
  Fly   126 EDQLLIVSKKVGLAEAATSTVNPTTAYRMLKDFVQLCPGDTVIQNGANSAVGQAVHQLCRAWGIN 190

Human   239 TINVVRDRPDIQKLSDRLKSLGAEHVITEEELRRPEMKNFFKIRKLRLRKEEMLNQNHIVYKGSR 303
            ::.:|||||:|.:|...|:.|||..|:||.|:|..::   ||..||   |:..|..|.:..|.:.
  Fly   191 SVGIVRDRPEIAELKQMLQCLGATEVLTEAEIRTSDI---FKSGKL---KKPRLAFNCVGGKSAT 249

Human   304 ESELASVSPNSKPLNLPEPPPHNMPRHAPATACSQLCWWEKLHRAAAAVSAWRNHGNLWGDGQAA 368
            |                      :.||..                        |.|.|...|..:
  Fly   250 E----------------------VSRHLD------------------------NGGVLVTYGGMS 268

Human   369 RRSLCEPSMSFLCLQSLLIFKDLKLRGFWLSQWKKDH--SPDQ---FKELILTLCDLIRRGQLTA 428
            |    ||   .......|||||:..||||:::|.|::  ||::   |||:.    :|:.:|:..|
  Fly   269 R----EP---VTVATGPLIFKDIAFRGFWMTRWSKENYSSPERSKMFKEIF----ELMEQGKFVA 322

Human   429 PACSQVPLQDYQSALEA--SMKPFISSKQILTM 459
            |....|||..::.|..|  |.|.|...|.||.|
  Fly   323 PNHEMVPLAKFKDAAAAALSFKGFTGKKYILDM 355

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MECR	XP_011539841.1	ETR	44..459	CDD:176250	156/421 (37%)
CG16935	NP_610914.2	ETR	23..355	CDD:176250	156/421 (37%)