Protein Alignment ABHD5 and CG2059

DIOPT Version :9

• Sequence 1: NP_001342115.1
• Gene: ABHD5 / 51099
• HGNCID: 21396
• Length: 349
• Species: Homo sapiens
• Sequence 2: NP_001188553.1
• Gene: CG2059 / 31663
• FlyBaseID: FBgn0029942
• Length: 308
• Species: Drosophila melanogaster
• Alignment Length: 315
• Identity: 75/315 - (23%)
• Similarity: 120/315 - (38%)
• Gaps: 59/315 - (18%)

Human    53 EPVRISNGNKIWTLKFSHNISNKTPLVLLHGFGGGLGLWALNFGDLC--TNRPVYAFDLLGFGRS 115
            :||.:|..:  :|   ..|.....||:..||..|....|......|.  .:|.|||.|:...|.|
  Fly    35 DPVELSFDS--YT---GENPETSPPLLTYHGLFGSKQNWRGISKALVRKVSRKVYAIDVRNHGES 94

Human   116 SRPRFDSDAEEVEN--QFVESIEEWRCALGLDKMILLGHNLGGFLAAAYSLKYPSRVNHLILVEP 178
            ......:.....|:  .|:|.......|       .:||::||.....::.|||..|..||:|
  Fly    95 PHSSVHNSKAMSEDLRLFMEQRSHPNAA-------CMGHSMGGRSMMYFARKYPELVERLIVV-- 150

Human   179 WGFPERPDLADQDRPIPVWIRALGAALTPFNPLAGLRIAGPFGLSLVQRLRPDFKRKYSSMFEDD 243
                   |::    ||.| .|:.|.....|:.:..|.::....:|..:::.   :.|.....||:
  Fly   151 -------DIS----PISV-PRSTGEMTEIFDAMVSLDLSPSMSMSEGRKIA---REKLLKATEDE 200

Human   244 TVTEYIYHCNVQTPSGETAFKNMTIPYGWA-----KRPMLQRIGKMHPDI--------PVSVIFG 295
            ||...:.:......:|         .:.||     .|..|.|..|...::        |.:.|.|
  Fly   201 TVDFIMLNLRKNPDTG---------AFSWACNAHVLREFLTRFDKYQSNLEELPPYTGPTTFICG 256

Human   296 ARS-CIDGNSGTSIQSLRPHSYVKTIAILGAGHYVYADQPEEFNQKVKEICDTVD 349
            .|| .:.......||.:.|:|   .|..|.|||.|:.::|:||...|.|..:..:
  Fly   257 TRSPYMRREQWPQIQKMFPNS---EIHWLDAGHLVHFEKPQEFLTIVSEFLNRTE 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ABHD5	NP_001342115.1	Abhydrolase_1	1..345	CDD:331148	75/309 (24%)
		HXXXXD motif	327..332		2/4 (50%)
CG2059	NP_001188553.1	PRK10673	38..305	CDD:182637	73/307 (24%)
		Abhydrolase_5	54..>151	CDD:289465	29/112 (26%)
		Abhydrolase	<253..287	CDD:304388	12/36 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910