Protein Alignment SCCPDH and CG2604

DIOPT Version :10

• Sequence 1: NP_057086.2
• Gene: SCCPDH / 51097
• HGNCID: 24275
• Length: 429
• Species: Homo sapiens
• Sequence 2: NP_649517.1
• Gene: CG2604 / 40623
• FlyBaseID: FBgn0037298
• Length: 430
• Species: Drosophila melanogaster
• Alignment Length: 436
• Identity: 172/436 - (39%)
• Similarity: 257/436 - (58%)
• Gaps: 33/436 - (7%)

Human    10 LVVFGASGFTGQFVTEEVAREQVDPERSSRLPWAVAGRSREKLQRVLEKAALKLGRPTLSSEVGI 74
            :::||||||||::...|.    |...|..|  |.:|||:||||:.||::...|..:..  |:|.|
  Fly     8 VIIFGASGFTGKYTVFEA----VTVLRGLR--WGIAGRNREKLEAVLKEMGAKAKKDL--SQVPI 64

Human    75 IICDIANPASLDEMAKQATVVLNCVGPYRFYGEPVIKACIENGASCIDISGEPQFLELMQLKYHE 139
            .|.|:.:.|||.||||:..:|:|..|||||:||.|:|.|||:|...:|:|||||::|.|||:|.:
  Fly    65 FIADVNDQASLLEMAKKCRIVVNTAGPYRFHGENVVKCCIESGTHHVDVSGEPQYMETMQLRYDQ 129

Human   140 KAADKGVYIIGSSGFDSIPADLGVIYTRNKMNGTLTAVESFLT--IHSGPEG---LSIHDGTWKS 199
            .|.:||||::.:.||||||||:||::.....:|.:.:||:||.  |..|..|   ..::.|||:|
  Fly   130 LAREKGVYVVSACGFDSIPADMGVVFVEKNFDGVVNSVETFLETGIKEGGSGGGTAGLNYGTWES 194

Human   200 AIYGFGDQSNLRKLRNVSNLKPVPLIGPKLKRRWPISYCRELKGYSIPFMGSDVSVVRRTQRYLY 264
            |:||......||.:|.....:.:|...|.||.|..:....|:....:||.|||.|||.|:||:||
  Fly   195 AVYGLAHSDELRGIRKQIYPQRLPRFYPFLKPRPLVFRSTEVDKVCLPFPGSDRSVVMRSQRFLY 259

Human   265 ENLEESPVQYAAYV------TVGGITSVIKLMFAGLFFLFFVRFGIGRQLLIKFPWFFSFGYFSK 323
            :..::.|||..|||      ..||:     :.||.:|.| ..:|.:||.||:.:|..||.|..|:
  Fly   260 DQDKKRPVQMQAYVGFSSWLVAGGV-----IFFATIFGL-LSKFKLGRTLLLNYPGLFSGGLASR 318

Human   324 QGPTQKQIDAASFTLTFFGQGY------SQGTGTDKNKPNIKICTQVKGPEAGYVATPIAMVQAA 382
            .||:::.::...|.:||...|:      ::.:......|...:..:|.|...||.||.:|::.||
  Fly   319 SGPSEESMERTYFKMTFKASGWLKSDRLAESSNQYTESPTKTLMVRVSGMNPGYGATCVAVLSAA 383

Human   383 MTLLSDASHLPKAGGVFTPGAAFSKTKLIDRLNK--HGIEFSVISS 426
            :|:|.::..:|..|||..|.||||||.||..|.|  |||:|.::::
  Fly   384 LTILRESDKMPSTGGVLPPAAAFSKTGLISELEKHDHGIKFEILAN 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SCCPDH	NP_057086.2	COG3268	1..425	CDD:442499	172/433 (40%)
CG2604	NP_649517.1	COG3268	1..428	CDD:442499	172/433 (40%)