Protein Alignment SEPSECS and Sply

DIOPT Version :10

• Sequence 1: NP_001397643.1
• Gene: SEPSECS / 51091
• HGNCID: 30605
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_652032.1
• Gene: Sply / 46059
• FlyBaseID: FBgn0010591
• Length: 545
• Species: Drosophila melanogaster
• Alignment Length: 358
• Identity: 71/358 - (19%)
• Similarity: 135/358 - (37%)
• Gaps: 79/358 - (22%)

Human   127 PENGWDESTLELFLHELAIMDSNNFLGNCGVGEREGRVASALVARRHYRFIHGIGRSGDISAVQP 191
            ||.|..:..:      |.::|.:...|:  ...|:|||:.|:           .|...|:..:..
  Fly   104 PEKGLSKEEI------LRLVDEHLKTGH--YNWRDGRVSGAV-----------YGYKPDLVELVT 149

Human   192 KAAG-SSLLNKITNSLVLDIIKLAG--VHTVANCF------VVPMATG--MSLTLCFLTLRHKRP 245
            :..| :|..|.:...|...:.|:..  |....|.|      ...|.||  .|:.:.....|....
  Fly   150 EVYGKASYTNPLHADLFPGVCKMEAEVVRMACNLFHGNSASCGTMTTGGTESIVMAMKAYRDFAR 214

Human   246 KAKYIIWPRIDQKSCFKSMITAGFEP------VVIENV-LEGDELRTDLKAVEAKVQELGPDCIL 303
            :.|.|..|.|    .....:.|.|:.      :.:.:| ::.:....|:|..:..:..   :.||
  Fly   215 EYKGITRPNI----VVPKTVHAAFDKGGQYFNIHVRSVDVDPETYEVDIKKFKRAINR---NTIL 272

Human   304 CIHSTTSCFAPRVP----DRLEELAVICANYDIPHIVNNAYGVQSSKCMHLIQQ-GARVGRIDAF 363
            .:.|     ||..|    |.:|.:|.:...||||..|:...|   |..:.|::. |.::...|..
  Fly   273 LVGS-----APNFPYGTIDDIEAIAALGVKYDIPVHVDACLG---SFVVALVRNAGYKLRPFDFE 329

Human   364 VQSL-------DKNFMVPVGGAIIAGFNDSFIQE----ISKMYPGRASASPSLD----------V 407
            |:.:       .|....|.|.::|. ::|...::    ::..:||....||:::          .
  Fly   330 VKGVTSISADTHKYGFAPKGSSVIL-YSDKKYKDHQFTVTTDWPGGVYGSPTVNGSRAGGIIAAC 393

Human   408 LITLLSLGSNGYKKLLKERKEMFSYLSNQIKKL 440
            ..|::|.|.:||.:..|...:...|:...::.:
  Fly   394 WATMMSFGYDGYLEATKRIVDTARYIERGVRDI 426

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SEPSECS	NP_001397643.1	selenium_SpcS	12..543	CDD:211833	71/358 (20%)
Sply	NP_652032.1	DOPA_deC_like	132..494	CDD:99743	63/322 (20%)