Protein Alignment SEPSECS and Hdc

DIOPT Version :10

• Sequence 1: NP_001397643.1
• Gene: SEPSECS / 51091
• HGNCID: 30605
• Length: 586
• Species: Homo sapiens
• Sequence 2: NP_523679.2
• Gene: Hdc / 36076
• FlyBaseID: FBgn0005619
• Length: 847
• Species: Drosophila melanogaster
• Alignment Length: 219
• Identity: 51/219 - (23%)
• Similarity: 83/219 - (37%)
• Gaps: 41/219 - (18%)

Human   278 LEGDELRTDLKAVEAKV-QELGPDCILCIHSTT-SCFAPRVPDRLEELAVICANYDIPHIVNNAY 340
            :.|..||   :|:|..: |.|.|..:.....|| ||..    |.|||:.::||.:.:...|:.||
  Fly   218 MRGKLLR---EAIEDDIKQGLVPFWVCATLGTTGSCSF----DNLEEIGIVCAEHHLWLHVDAAY 275

Human   341 GVQSSKCMHLIQQGARVGRIDAFVQSLDKNFMVPVGG---------AIIAGFNDSFIQEISKMYP 396
            ...:..|.........:.|.|:...:..|..||....         |:...||      :..:|.
  Fly   276 AGSAFICPEFRTWLRGIERADSIAFNPSKWLMVHFDATALWVRDSTAVHRTFN------VEPLYL 334

Human   397 GRASASPSLDVLITLLSLGSNGYKKLLKERKEMFSYLSNQIKKLSEAYNERLLHTPHNPISLAMT 461
            ...::..::|.:...:.| |..::.|    |..|...|..||.|.....|        .:.||..
  Fly   335 QHENSGVAVDFMHWQIPL-SRRFRAL----KVWFVLRSYGIKGLQRHIRE--------GVRLAQK 386

Human   462 LK--TLDEHRDK--AVTQLGSMLF 481
            .:  .|.:||.:  |...||.::|
  Fly   387 FEALVLADHRFELPAKRHLGLVVF 410

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SEPSECS	NP_001397643.1	selenium_SpcS	12..543	CDD:211833	51/219 (23%)
Hdc	NP_523679.2	Pyridoxal_deC	35..413	CDD:395219	51/219 (23%)