Protein Alignment CRYL1 and Had1

DIOPT Version :10

• Sequence 1: NP_057058.2
• Gene: CRYL1 / 51084
• HGNCID: 18246
• Length: 319
• Species: Homo sapiens
• Sequence 2: NP_573114.2
• Gene: Had1 / 32592
• FlyBaseID: FBgn0286508
• Length: 315
• Species: Drosophila melanogaster
• Alignment Length: 308
• Identity: 160/308 - (51%)
• Similarity: 218/308 - (70%)
• Gaps: 2/308 - (0%)

Human     9 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSVEEQLS 73
            |.|||||:|||||:|||||.|:||.||||..:|:..||...:||::.||..|.|:|.|:..:|.:
  Fly     8 VGIVGSGLIGRSWSMLFASVGYQVVLYDILPEQVSTALTATQKELQDLEAKGLLRGKLTAAQQFA 72

Human    74 LISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHV 138
            .|||..:::|.|:||:.:|||:||.|:|||.::.|||:::....|||||||..:||...|.|.:.
  Fly    73 CISGTNDLKELVKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTSTFLPSLFSADLKNK 137

Human   139 KQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAII 203
            ...:|:||||||||:||||:||.|.|.|..|.:|.|||::|||.|:.:.:|:.||.|||:||||:
  Fly   138 ANVLVSHPVNPPYYVPLVEIVPAPWTKPEWVKKTRALMEEIGQKPVTLSREIEGFALNRIQYAIL 202

Human   204 SEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVLQTFGP 268
            :|.|||||.||::..|:|.|||.|||.||||:|||||.|||||||.:|.:|||..|..|.:|.||
  Fly   203 NETWRLVEAGILNVKDIDSVMSNGLGPRYAFLGPLETAHLNAEGMANYFERYSNTIYAVSETMGP 267

Human   269 IPEFSRATAEKVNQDMCMKVPDDPEHLAARRQWRDECLMRLAKLKSQV 316
            .|:.....|.:|.:.:...||.|  .||.||.:||.||.:|:.||:::
  Fly   268 TPKMEGPVAVEVAKQLGEMVPLD--QLAQRRNYRDNCLTQLSILKNKL 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CRYL1	NP_057058.2	PRK06129	9..314	CDD:235706	159/304 (52%)
Had1	NP_573114.2	PRK06129	7..310	CDD:235706	158/303 (52%)