Protein Alignment TMX2 and tmx2b

DIOPT Version :10

• Sequence 1: NP_001334819.1
• Gene: TMX2 / 51075
• HGNCID: 30739
• Length: 303
• Species: Homo sapiens
• Sequence 2: NP_001002113.1
• Gene: tmx2b / 415203
• ZFINID: ZDB-GENE-040625-105
• Length: 307
• Species: Danio rerio
• Alignment Length: 314
• Identity: 215/314 - (68%)
• Similarity: 257/314 - (81%)
• Gaps: 18/314 - (5%)

Human     1 MAVLAPLIALVYSVPRLSRWLAQPYYLLSALLSAAFLLVRKLPPLCHGLPTQREDGNPCDFDWRE 65
            ||:|.||.|.:|.:|::.:||.:|||:.|..:|.||:::||:|.:|..|.|||||||.|||||||
Zfish     1 MALLTPLFAFLYHLPQVYKWLLKPYYIASLFMSIAFVMIRKMPGVCEHLSTQREDGNSCDFDWRE 65

Human    66 VEILMFLSAIVMMKNRRSITVEQHIGNIFMFSKVANTILFFRLDIRMGLLYITLCIVFLMTCKPP 130
            |||||||||||||||||:||:|||:|||.:|.||||.|||||||||:||||:|||||||||||||
Zfish    66 VEILMFLSAIVMMKNRRAITIEQHVGNIILFCKVANVILFFRLDIRLGLLYLTLCIVFLMTCKPP 130

Human   131 LYMGPEYIKYFNDKTIDEELERDKRVTWIVEFFANWSNDCQSFAPIYADLSLKYNCTGLNFGKVD 195
            |||||||||||:|||||||||:|.|||||||||||||.:|||||.:||||||||||.||.|||||
Zfish   131 LYMGPEYIKYFSDKTIDEELEKDHRVTWIVEFFANWSPECQSFASVYADLSLKYNCAGLKFGKVD 195

Human   196 VGRYTDVSTRELSGPCRYKVSTSPLTKQLPTLILFQGGKEAMRRPQIDKKGRAVSWTFSEENVIR 260
            :|||.:||.       :|:||||||:||||:|:|||||||.|||||:|||||||||||:|||:||
Zfish   196 IGRYGEVSK-------KYRVSTSPLSKQLPSLVLFQGGKEVMRRPQVDKKGRAVSWTFTEENIIR 253

Human   261 EFNLNELYQRAKKLSKAGD-----------NIPEEQPVASTPTTVSDGENKKDK 303
            |||||||||::|||.|..:           .:|||:...:...:..|.|:||||
Zfish   254 EFNLNELYQKSKKLGKTKEKLERPSELVFSTVPEEEEPEAETISAMDTESKKDK 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TMX2	NP_001334819.1	TMX2	109..266	CDD:239260	125/156 (80%)
tmx2b	NP_001002113.1	TMX2	109..259	CDD:239260	125/156 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	268..307		8/38 (21%)
		Di-lysine motif. /evidence=ECO:0000305	304..307		2/2 (100%)