Protein Alignment EXOSC3 and Exosc3

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_079789.1
• Gene: Exosc3 / 66362
• MGIID: 1913612
• Length: 274
• Species: Mus musculus
• Alignment Length: 275
• Identity: 240/275 - (87%)
• Similarity: 253/275 - (92%)
• Gaps: 1/275 - (0%)

Human     1 MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRV 65
            |||..|...||:||.||||...||.|||||||||:||:.||.:|.|||.|:||.|||.|..|:||
Mouse     1 MAEVLSAGPESVAGCRARAVHKVLNQVVLPGEELVLPDHEDVDGLGGAGEQPLRLNAGARPRLRV 65

Human    66 VCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFK 130
            |||||||||||||||||||||||||| ||.||||||||||||||||||||||||||.||||||||
Mouse    66 VCGPGLRRCGDRLLVTKCGRLRHKEP-SGGGGGVYWVDSQQKRYVPVKGDHVIGIVIAKSGDIFK 129

Human   131 VDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQ 195
            ||||||||||||||:|||||||||||||||||||||.||||||||||||||||||||||||||||
Mouse   130 VDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRANGMGVIGQ 194

Human   196 DGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHM 260
            ||||||||||||||||||||||:||:|||||||||||||||||||||||||||||||:|||||||
Mouse   195 DGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILANVLEACEHM 259

Human   261 TSDQRKQIFSRLAES 275
            |::||||||:|||||
Mouse   260 TTEQRKQIFARLAES 274

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	81/84 (96%)
		KH-I_Rrp40	196..273	CDD:411954	70/76 (92%)
Exosc3	NP_079789.1	S1_Rrp40	107..192	CDD:240216	81/84 (96%)
		KH-I_Rrp40	195..272	CDD:411954	70/76 (92%)