Protein Alignment EXOSC3 and exosc3

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_001025132.2
• Gene: exosc3 / 565000
• ZFINID: ZDB-GENE-050706-140
• Length: 247
• Species: Danio rerio
• Alignment Length: 254
• Identity: 154/254 - (60%)
• Similarity: 195/254 - (76%)
• Gaps: 25/254 - (9%)

Human    24 LGQVVLPGEELLL---PEQEDAEGPGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGR 85
            :|.|||||:.|..   ||..||             |.:|   .|::|||||||.|..:.|.:.|.
Zfish    13 IGDVVLPGDLLFSFSPPEAGDA-------------NPKA---DRLICGPGLRRSGAEIRVCRAGV 61

Human    86 LRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGAT 150
            |:||:|      .:|||:.||:||||.||:.|||||||||||:|||||||||.||||||:|||||
Zfish    62 LKHKQP------NMYWVNCQQRRYVPAKGESVIGIVTAKSGDVFKVDVGGSEQASLSYLAFEGAT 120

Human   151 KRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDC 215
            ||||||||||||::|||.:||||||||:||||||||||||||.|.|||||||:|||:|:||||..
Zfish   121 KRNRPNVQVGDLVFGQFTIANKDMEPELVCIDSCGRANGMGVFGGDGLLFKVSLGLVRRLLAPQS 185

Human   216 EIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAE 274
            :::.::.|::|.|:|.|||||:||||:|:|.||||:|:|||.|:|::.||..:|||:|:
Zfish   186 DLVSDLEKMFPCEMVVGMNGRVWVKARTVQHTLILSNLLEASENMSTAQRHTLFSRVAD 244

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	73/84 (87%)
		KH-I_Rrp40	196..273	CDD:411954	45/76 (59%)
exosc3	NP_001025132.2	None