Protein Alignment EXOSC3 and Exosc3

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_001101406.2
• Gene: Exosc3 / 313243
• RGDID: 1304739
• Length: 282
• Species: Rattus norvegicus
• Alignment Length: 283
• Identity: 240/283 - (84%)
• Similarity: 254/283 - (89%)
• Gaps: 9/283 - (3%)

Human     1 MAEPASVAAESLAGSRARAARTVLGQVVLPGEELLLPEQEDAEGPGGAVERPLSLNARACSRVRV 65
            ||| .|..|||:||.||||...||.|||||||||:||:.|||:|.||..|:||.|||.|..|:|:
  Rat     1 MAE-VSAGAESVAGCRARAVHKVLNQVVLPGEELVLPDHEDADGLGGPGEQPLRLNAGARPRLRI 64

Human    66 VCGPGLRRCGDRLLVTKCGRLRHKEP--------GSGSGGGVYWVDSQQKRYVPVKGDHVIGIVT 122
            ||||||||||||||||||||||||||        |.|.||||||||||||||||||||||||||.
  Rat    65 VCGPGLRRCGDRLLVTKCGRLRHKEPSGGGGGGGGGGGGGGVYWVDSQQKRYVPVKGDHVIGIVV 129

Human   123 AKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRA 187
            ||||||||||||||||||||||:|||||||||||||||||||||.||||||||||||||||||||
  Rat   130 AKSGDIFKVDVGGSEPASLSYLAFEGATKRNRPNVQVGDLIYGQCVVANKDMEPEMVCIDSCGRA 194

Human   188 NGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILAN 252
            ||||||||||||||||||||||||||||||:||:|||||||||||||||||||||||||||||||
  Rat   195 NGMGVIGQDGLLFKVTLGLIRKLLAPDCEIVQELGKLYPLEIVFGMNGRIWVKAKTIQQTLILAN 259

Human   253 ILEACEHMTSDQRKQIFSRLAES 275
            :||||||||::||||||:|||||
  Rat   260 VLEACEHMTTEQRKQIFARLAES 282

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	81/84 (96%)
		KH-I_Rrp40	196..273	CDD:411954	70/76 (92%)
Exosc3	NP_001101406.2	S1_Rrp40	115..200	CDD:240216	81/84 (96%)
		KH-I_Rrp40	203..280	CDD:411954	70/76 (92%)