Protein Alignment EXOSC3 and rrp40

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_593242.1
• Gene: rrp40 / 2541837
• PomBaseID: SPAC22A12.12C
• Length: 240
• Species: Schizosaccharomyces pombe
• Alignment Length: 214
• Identity: 71/214 - (33%)
• Similarity: 125/214 - (58%)
• Gaps: 15/214 - (7%)

Human    68 GPGL----RRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDI 128
            ||||    :...:.::|:|.|||..      :|.....:||:.|||:|...|.|||.:.::..:.
pombe    33 GPGLVFQKKDREEEIVVSKAGRLHQ------TGKNAMLIDSRTKRYIPATNDQVIGQIISRFAEG 91

Human   129 FKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDMEPEMVCID-SCGRANGMGV 192
            ::||:|.:..|.|:.|:||..|:::|||:.||.|:|.:..:|::|||||:.|.| :.|:|.|.|.
pombe    92 YRVDIGSAHIAQLNALAFENVTRKSRPNLNVGSLVYARVSLADRDMEPELECFDATTGKAAGYGE 156

Human   193 IGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEAC 257
            :....::..::|...|||:.|...::|.:|...|.||..|||||:||.::.:..|:::...:..|
pombe   157 LKNGYMITGLSLSHCRKLILPKNTLLQTLGSYIPFEIAVGMNGRVWVNSENLSTTVLICTAIRNC 221

Human   258 EHMTSDQR----KQIFSRL 272
            |.|:.:::    |.:..:|
pombe   222 EFMSDEEQIKYCKDLIKKL 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	35/85 (41%)
		KH-I_Rrp40	196..273	CDD:411954	23/81 (28%)
rrp40	NP_593242.1	S1_Rrp40	71..157	CDD:240216	35/85 (41%)
		KH-I_Rrp40	160..237	CDD:411954	22/76 (29%)