Protein Alignment EXOSC3 and exos-3

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: NP_492751.1
• Gene: exos-3 / 186604
• WormBaseID: WBGene00010325
• Length: 226
• Species: Caenorhabditis elegans
• Alignment Length: 219
• Identity: 82/219 - (37%)
• Similarity: 125/219 - (57%)
• Gaps: 15/219 - (6%)

Human    45 PGGAVERPLSLNARACSRVRVVCGPGLRRCGDRLLVTKCGRLRHKEPGSGSGGGVYWVDSQQKRY 109
            ||..:..|.|.::.       :.|.|:...|...:.|:.|...:.:       |..|::...|||
 Worm     6 PGDVINEPSSSDSS-------IIGYGISVRGQTRIATQPGAFHNDD-------GKVWLNVHSKRY 56

Human   110 VPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATKRNRPNVQVGDLIYGQFVVANKDM 174
            :|.:||.||.|||:|:||.|::|:|.:|.|.:::.:|||||||||||::.||:||..........
 Worm    57 IPQEGDRVIAIVTSKTGDFFRLDIGTAEYAMINFTNFEGATKRNRPNLKTGDIIYATVFDTTPRT 121

Human   175 EPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCEIIQEVGKLYPLEIVFGMNGRIWV 239
            |.|:.|:|...||.|||.: ..|.:|||:|...|:|:.|.|:|:|.|||.:..||..|||||||:
 Worm   122 EAELTCVDDEKRARGMGQL-NGGFMFKVSLNHCRRLINPSCKILQTVGKFFKFEITVGMNGRIWI 185

Human   240 KAKTIQQTLILANILEACEHMTSD 263
            .|.|....:.:.:|:...|.:|.:
 Worm   186 SASTSDDIIKIHDIINKSEFITDE 209

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	42/84 (50%)
		KH-I_Rrp40	196..273	CDD:411954	28/68 (41%)
exos-3	NP_492751.1	S1_Rrp40	55..140	CDD:240216	42/84 (50%)
		KH-I_Rrp40	142..210	CDD:411954	28/68 (41%)