Protein Alignment EXOSC3 and exosc3

DIOPT Version :10

• Sequence 1: NP_057126.2
• Gene: EXOSC3 / 51010
• HGNCID: 17944
• Length: 275
• Species: Homo sapiens
• Sequence 2: XP_002936379.2
• Gene: exosc3 / 100491278
• XenbaseID: XB-GENE-966926
• Length: 250
• Species: Xenopus tropicalis
• Alignment Length: 254
• Identity: 171/254 - (67%)
• Similarity: 208/254 - (81%)
• Gaps: 17/254 - (6%)

Human    24 LGQVVLPGEELLLPEQ-EDAEGPGGAVERPLSLNARACS-RVRVVCGPGLRRCGDRLLVTKCGRL 86
            :||:||||:.|:|..| .||         ||||:..:.| |.||||||||.|..|.|||.|||.|
 Frog    10 VGQIVLPGDVLVLSTQSRDA---------PLSLSGPSTSNRPRVVCGPGLMRQEDDLLVNKCGLL 65

Human    87 RHKEPGSGSGGGVYWVDSQQKRYVPVKGDHVIGIVTAKSGDIFKVDVGGSEPASLSYLSFEGATK 151
            ||::|      .:|||||||||||||||||||||||.||||||||||||||.||||||:||||||
 Frog    66 RHRDP------AIYWVDSQQKRYVPVKGDHVIGIVTTKSGDIFKVDVGGSEQASLSYLAFEGATK 124

Human   152 RNRPNVQVGDLIYGQFVVANKDMEPEMVCIDSCGRANGMGVIGQDGLLFKVTLGLIRKLLAPDCE 216
            :|||||:||||:||||:||||||||||.||||.|:|||.||||||||:.||:|||:||||.|..:
 Frog   125 KNRPNVKVGDLVYGQFIVANKDMEPEMACIDSSGKANGKGVIGQDGLMLKVSLGLVRKLLIPQND 189

Human   217 IIQEVGKLYPLEIVFGMNGRIWVKAKTIQQTLILANILEACEHMTSDQRKQIFSRLAES 275
            |:||:..::|:|:|.||||||||||||:|||||:||:|||||::|::|||.:||:.:::
 Frog   190 IVQELMNIFPMEVVIGMNGRIWVKAKTVQQTLIVANLLEACEYLTAEQRKHVFSKFSDN 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EXOSC3	NP_057126.2	S1_Rrp40	108..193	CDD:240216	73/84 (87%)
		KH-I_Rrp40	196..273	CDD:411954	49/76 (64%)
exosc3	XP_002936379.2	S1_Rrp40	81..166	CDD:240216	73/84 (87%)
		KH-I_Rrp40	169..246	CDD:411954	49/76 (64%)