Protein Alignment ACOX1 and Acox1

DIOPT Version :10

• Sequence 1: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_059036.1
• Gene: Acox1 / 50681
• RGDID: 619757
• Length: 661
• Species: Rattus norvegicus
• Alignment Length: 666
• Identity: 570/666 - (85%)
• Similarity: 610/666 - (91%)
• Gaps: 11/666 - (1%)

Human     1 MNPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDFQHEDLNFLTRSQRYEVAVR 65
            ||||||:||.||:|||||:|||||||||.|||||||||:|||||||||||.|||||||||||||:
  Rat     1 MNPDLRKERASATFNPELITHILDGSPENTRRRREIENLILNDPDFQHEDYNFLTRSQRYEVAVK 65

Human    66 KSAIMVKKMREFGIADPDEIMWFK-----NFVHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFM 125
            |||.|||||||:||:||:||||||     |||     ||:.|:..||:||||:|.|..|||::..
  Rat    66 KSATMVKKMREYGISDPEEIMWFKKLYLANFV-----EPVGLNYSMFIPTLLNQGTTAQQEKWMR 125

Human   126 PAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVL 190
            |:..|:|||||||||||||||||||||||||||:|||||||||||||||||||||||||||||||
  Rat   126 PSQELQIIGTYAQTEMGHGTHLRGLETTATYDPKTQEFILNSPTVTSIKWWPGGLGKTSNHAIVL 190

Human   191 AQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMK 255
            |||||:|:|||||||:||||||||||||||||||||||||||:|:|||||||||:||||||||||
  Rat   191 AQLITQGECYGLHAFVVPIREIGTHKPLPGITVGDIGPKFGYEEMDNGYLKMDNYRIPRENMLMK 255

Human   256 YAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQ 320
            ||||||||||||||||||||||||||||||||.||::|||||||||||||||.|||||..|||||
  Rat   256 YAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGNAAQSLSKACTIAIRYSAVRRQSEIKQSEPEPQ 320

Human   321 ILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTA 385
            |||||||||||||||||||||.|||.||||||.||||.|||||||||||||||||||||||:|||
  Rat   321 ILDFQTQQYKLFPLLATAYAFHFVGRYMKETYLRINESIGQGDLSELPELHALTAGLKAFTTWTA 385

Human   386 NTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSGKLVCG 450
            |.|||.||||||||||||.||:|||||.|||:||||||||||||||||||||.||||.|||||.|
  Rat   386 NAGIEECRMACGGHGYSHSSGIPNIYVTFTPACTFEGENTVMMLQTARFLMKIYDQVRSGKLVGG 450

Human   451 MVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVA 515
            |||||||||||||||||||||||||||||.|.|||||||||||||||||||||..|.||||||||
  Rat   451 MVSYLNDLPSQRIQPQQVAVWPTMVDINSLEGLTEAYKLRAARLVEIAAKNLQTHVSHRKSKEVA 515

Human   516 WNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLLYSLYGISQNAGDFLQGSIM 580
            ||||||||||||||||||||||:||:||.||||||:|||||:||||||||||||..||||:|||:
  Rat   516 WNLTSVDLVRASEAHCHYVVVKVFSDKLPKIQDKAVQAVLRNLCLLYSLYGISQKGGDFLEGSII 580

Human   581 TEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNKAE 645
            |..|::|||.|:.|||||||.:||||||||||:|:||||||||||||||||||||||.|||||.|
  Rat   581 TGAQLSQVNARILELLTLIRPNAVALVDAFDFKDMTLGSVLGRYDGNVYENLFEWAKKSPLNKTE 645

Human   646 VHESY-KHLKSLQSKL 660
            ||||| ||||.|||||
  Rat   646 VHESYHKHLKPLQSKL 661

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	546/638 (86%)
Acox1	NP_059036.1	AXO	3..638	CDD:173839	547/639 (86%)
		Microbody targeting signal. /evidence=ECO:0000255	659..661		1/1 (100%)