Protein Alignment ACOX1 and Mcad

DIOPT Version :9

• Sequence 1: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_648149.1
• Gene: Mcad / 38864
• FlyBaseID: FBgn0035811
• Length: 419
• Species: Drosophila melanogaster
• Alignment Length: 479
• Identity: 104/479 - (21%)
• Similarity: 170/479 - (35%)
• Gaps: 158/479 - (32%)

Human    19 LTHILDGSPEKTRRRREIENMILNDPDFQHEDL-NFLTRSQRYEVAVR--KSA----IMVKKMRE 76
            ::|:   ||..|       :..|.:...|.::| ...||.:...||.:  ||.    .::||..|
  Fly    25 VSHV---SPNGT-------SFALTEDQLQLQELARKFTREEIIPVAAQYDKSGEYPWPIIKKAWE 79

Human    77 FGIADPDEIMWFKNFVHRGRPEPLD---LHLGMFLPTLLHQATA--------------------- 117
            .|:        ..|.:      |.|   |.|.:|...|..:..|
  Fly    80 LGL--------MNNHI------PADIGGLDLDVFTTCLSAEELAYGCTGIMTALEASGLGQTPVI 130

Human   118 -----EQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWW- 176
                 ||::::........::..|..||.|.|:.:.|::|.|  :.:..|:::|..     |.|
  Fly   131 LSGNKEQKKKYLGRLLEEPLVAAYCVTEPGAGSDVSGIKTRA--EKKGDEWVINGQ-----KMWI 188

Human   177 -PGGLGKTSNHAIVLAQLITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYL 240
             .||:   :|...|||:.....||....||...|.|    :..||:|.|......|....|...:
  Fly   189 TNGGV---ANWYFVLARTNPDPKCPPSKAFTGFIVE----RDSPGLTPGRKELNMGQRASDTRGI 246

Human   241 KMDNHRIPRENMLM------KYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTI 299
            ..::.|:|:||:|:      |.|.    ||:.|         |...|.:..||.|.|.|.:
  Fly   247 TFEDVRVPKENVLIGEGAGFKIAM----GTFDK---------TRPPVAAGAVGLAQRCLDE---- 294

Human   300 AIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPL-LATAYAFQFVGAYMK---ETYH------- 353
            |::|:..|                      |.|.: :|...|.||:.|.|.   ||..
  Fly   295 ALKYALER----------------------KTFGVPIAYHQAVQFMLADMAIGVETSRLAWRLSA 337

Human   354 -RINEGIGQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLP--------N 409
             .|::|......:.:.:.||.....|     .|:..::    ..||:|::  |..|        .
  Fly   338 WEIDQGRRNSYYASIAKCHAADMANK-----IASDAVQ----IFGGNGFN--SEYPVEKLMRDAK 391

Human   410 IYVNFTPSCTFEGENTVMMLQTAR 433
            ||.      .:||.:.:..|..:|
  Fly   392 IYQ------IYEGTSQIQRLIISR 409

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	104/479 (22%)
		PLN02443	5..651	CDD:178062	104/479 (22%)
Mcad	NP_648149.1	CaiA	35..411	CDD:224871	100/459 (22%)
		MCAD	37..414	CDD:173846	100/457 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810