Protein Alignment ACOX1 and CG7461

DIOPT Version :9

• Sequence 1: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_001286611.1
• Gene: CG7461 / 37217
• FlyBaseID: FBgn0034432
• Length: 627
• Species: Drosophila melanogaster
• Alignment Length: 647
• Identity: 134/647 - (20%)
• Similarity: 235/647 - (36%)
• Gaps: 132/647 - (20%)

Human     1 MNPDLRRERDSASFNPELLTHILDGS---------PE-KTRRRREIENMILNDPDFQHEDLNFLT 55
            :..:..|.::.||.|...:.:|..||         |: .|..::|:.|.:::..:....|:|...
  Fly    29 LGAESNRSKEKASENESFMANIFRGSLVSSQVFPYPDVLTAEQKELTNSLIDPFERFFSDVNDAA 93

Human    56 RSQRYEVAVRKSAIMVKKMREFGIADPDEIMWF-KNFVHRGRPEPL----DLHLGM--------- 106
            |:.........::..:.::..|||..|.|.... .|....||...:    ||.||:
  Fly    94 RNDANSKIDDTTSTALWELGAFGIQVPSEFGGLGLNNTQYGRLCAIVGVNDLGLGITIGAHQSIG 158

Human   107 FLPTLLHQATAEQQERFFMPAWNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVT 171
            |...||: .|.||:|::.......::...:|.||...|:....:...|....:.:.::||..
  Fly   159 FKGILLY-GTPEQKEKYLPKVAAEQVYAAFALTEPSSGSDAGSIRCRAVKSADGKHYVLNGS--- 219

Human   172 SIKWW--PGGLGKTSNHAIVLAQL-----ITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPK 229
              |.|  .||:.:...   |.||.     .|..|...:.||||. |..|      |:|.|....|
  Fly   220 --KIWISNGGIAEIMT---VFAQTEQVDPKTGEKKDKVTAFIVE-RSFG------GVTNGPPEKK 272

Human   230 FGYDEIDNGYLKMDNHRIPRENMLMKYAQVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALS 294
            .|....:...:..::.:||.||:|.|      :|...|...|.|..|      .|.:|.......
  Fly   273 MGIKASNTAEVYFEDVKIPIENVLGK------EGDGFKVAMNILNNG------RFGMGATLSGTM 325

Human   295 KACTIAIRYSAVRHQSEIKPGEPEPQILDFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGI 359
            |.|   |..:.....:.::.|:   ::.::.:.|.||..:....||.:.:.       ..|::.:
  Fly   326 KKC---IEQATEHANNRVQFGQ---KLKNYGSIQEKLAQMNILQYATESMA-------FTISQNM 377

Human   360 GQGDLSELPELHALTAGLKAFTSWTANTGIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGEN 424
            ..|.    .:.|...|..|.:.|.:|....:......||.||...:||..:..:......|||.|
  Fly   378 DAGS----KDYHLEAAISKIYASESAWYVCDEAIQILGGMGYMVDNGLERVLRDLRIFRIFEGTN 438

Human   425 TVMMLQTARFLMKSYDQVHSGKLVCGMVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKL 489
            .::.|..|.          :|....|  |:|.:|......|          ..|......||.:
  Fly   439 DILRLFIAL----------TGIQYAG--SHLKELQRAFKNP----------SANLGLIFKEASR- 480

Human   490 RAARLVEIAAKNLQKEVIHRKSKEVAWNLTSVDLVRASE--AHCHYVVVKLFSEKLLKIQDKAIQ 552
            |||..|.:...:|...|:.             :|:..::  |||    :.||.:.:.::..:..:
  Fly   481 RAASTVGLGGTDLSGHVVG-------------ELLPYAKKTAHC----IDLFGQSVEELLLRYNK 528

Human   553 AVLRSLCLLYSLYGISQNAGDFLQGSIMTEPQ----------ITQVNQRVKELLTLIRSDAV 604
            .::....||..|    .||...:...::|:.:          ..|....:.:.||:..||.|
  Fly   529 NIVNEQILLTRL----ANAAIDIYAMVVTQSRSSRAVNLNLPTAQHELNMTKALTIQASDRV 586

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	134/645 (21%)
		PLN02443	5..651	CDD:178062	134/643 (21%)
CG7461	NP_001286611.1	VLCAD	45..454	CDD:173850	98/463 (21%)
		CaiA	67..446	CDD:224871	92/423 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1960
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810