Protein Alignment ACOX1 and acox-1.3

DIOPT Version :10

• Sequence 1: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_493263.1
• Gene: acox-1.3 / 184167
• WormBaseID: WBGene00008566
• Length: 660
• Species: Caenorhabditis elegans
• Alignment Length: 667
• Identity: 282/667 - (42%)
• Similarity: 404/667 - (60%)
• Gaps: 27/667 - (4%)

Human     2 NPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDF-QHEDLNFLTRSQRYEVAVR 65
            |.||..||.:|:|:.:.:..::.|..|...|||::...|....:. :.:.|.|:||.::...:.|
 Worm     9 NSDLTEERKNATFDTDKMAAVIYGREEIASRRRQLTESISRIHELAESKPLVFMTREEKIAESCR 73

Human    66 KSAIMVKKMRE--FGIADPDEIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFMPAW 128
            |..::.:...:  |...:.::.:.....|......||.||..||:|||:.||:.||||::...|.
 Worm    74 KLEVLSRHWNQTPFNRDNEEDALHIYREVLGMEGHPLALHDTMFIPTLVAQASQEQQEKWLGRAR 138

Human   129 NLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQL 193
            ..||||.||||||||||:||.|||||||.|:|||||||:||:|::|||||.|||:||:|||:|.|
 Worm   139 RKEIIGCYAQTEMGHGTNLRKLETTATYSPDTQEFILNTPTITALKWWPGALGKSSNNAIVVANL 203

Human   194 ITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYAQ 258
            :.|.:.||.|.|:|.:|:..||.||.||.|||||||..::..|||||..:||||||.|:||::.:
 Worm   204 LIKDQNYGPHPFMVQLRDEKTHIPLKGIVVGDIGPKMAFNGADNGYLGFNNHRIPRTNLLMRHTK 268

Human   259 VKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQILD 323
            |:.:|||:||...|:.|.:||.|||.:..:....|:.|..||:||||||.|..::....:.::||
 Worm   269 VEANGTYIKPSHAKIGYSSMVKVRSRMAMDQGLFLASALVIAVRYSAVRRQGFLEDKTQKVKVLD 333

Human   324 FQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANTG 388
            :||||::|||.||.||||.|.|......|.::.:.:..|:.|.:.:|||||:|||:..:.....|
 Worm   334 YQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVTHQTGEG 398

Human   389 IEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSG--KLVCGM 451
            ||..|||||.||||..|.:..||......||:||||.||:||.||:|:||.:.:.||  |.:..|
 Worm   399 IEQARMACGEHGYSMASYISEIYGVAIGGCTYEGENMVMLLQLARYLVKSVELIKSGEEKKLGPM 463

Human   452 VSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVAW 516
            ||||             |......|::|......|::..|.|....|.:...|.:...:|:||||
 Worm   464 VSYL-------------AAKGGHPDLSSLNGYVTAFEHMARRQAWKATEKFLKLMETGESREVAW 515

Human   517 NLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLL---YSLYGISQNAGDFLQGS 578
            |.::|:|.|||..|....:::.|..::.:|:|..::.||..|..|   |.|..::..|.:|
 Worm   516 NKSAVELTRASRLHTRLFIIEAFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALEF---- 576

Human   579 IMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLNK 643
             |:..|:..:..::...|..||..||:|||:|...|:.|.|||||.|||||||||:|||:|||||
 Worm   577 -MSSTQLDYIRDQLYLYLEKIRPSAVSLVDSFQISDMQLRSVLGRRDGNVYENLFKWAKSSPLNK 640

Human   644 AEVHESY-KHLKSLQSK 659
            ::|..|. |:||.:..|
 Worm   641 SDVLPSVDKYLKPMMEK 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	268/641 (42%)
acox-1.3	NP_493263.1	ACAD	11..634	CDD:447864	268/640 (42%)