Protein Alignment ACOX1 and acox-1.4

DIOPT Version :10

• Sequence 1: NP_004026.2
• Gene: ACOX1 / 51
• HGNCID: 119
• Length: 660
• Species: Homo sapiens
• Sequence 2: NP_493264.1
• Gene: acox-1.4 / 173164
• WormBaseID: WBGene00008567
• Length: 662
• Species: Caenorhabditis elegans
• Alignment Length: 668
• Identity: 283/668 - (42%)
• Similarity: 399/668 - (59%)
• Gaps: 30/668 - (4%)

Human     2 NPDLRRERDSASFNPELLTHILDGSPEKTRRRREIENMILNDPDF-QHEDLNFLTRSQRYEVAVR 65
            ||||..||:..:|:.:.:..::.||.:..||||||...:...|:. ..:...|:.|.::.....|
 Worm    12 NPDLTEEREKGTFDTDKMAAVIYGSEKLARRRREISEAVSKIPELADTQPFPFMDRLEKITEGSR 76

Human    66 KSAIMVKKMREFGIADPD---EIMWFKNFVHRGRPEPLDLHLGMFLPTLLHQATAEQQERFFMPA 127
            |..::...:|:  |.|.|   |.:.....|......||.||..||:|.|:.||:.||||::...|
 Worm    77 KLEVLNNNIRD--IIDYDDNGERLHIYQEVTGMEGHPLALHEVMFIPALVSQASKEQQEKWLGRA 139

Human   128 WNLEIIGTYAQTEMGHGTHLRGLETTATYDPETQEFILNSPTVTSIKWWPGGLGKTSNHAIVLAQ 192
            ...||||.||||||||||:||.|||||||.|:||||:||:||.|::|||||.|||:||:|:|:..
 Worm   140 RRREIIGCYAQTEMGHGTNLRKLETTATYFPDTQEFVLNTPTTTALKWWPGALGKSSNYAVVVVD 204

Human   193 LITKGKCYGLHAFIVPIREIGTHKPLPGITVGDIGPKFGYDEIDNGYLKMDNHRIPRENMLMKYA 257
            :|.|||.||.|.|:|.:|:..||.||.||.|||||||..::..|||:|..|..|:||.|:||::.
 Worm   205 MIIKGKSYGPHPFMVQLRDEKTHIPLKGIVVGDIGPKMSFNGGDNGFLGFDKFRVPRTNLLMRHV 269

Human   258 QVKPDGTYVKPLSNKLTYGTMVFVRSFLVGEAARALSKACTIAIRYSAVRHQSEIKPGEPEPQIL 322
            :|:.|||||||...|:.:..||.|||.:.......|::|..||:||||||.|..::....|.::|
 Worm   270 RVEADGTYVKPPHAKVNHSAMVHVRSHMATGQGALLAQALIIAVRYSAVRRQGFLENKTQEVKVL 334

Human   323 DFQTQQYKLFPLLATAYAFQFVGAYMKETYHRINEGIGQGDLSELPELHALTAGLKAFTSWTANT 387
            |:||||::|||.||.||||.|.|......|.::.:.:..|:.|.:.:|||||:|||:..:.....
 Worm   335 DYQTQQHRLFPSLARAYAFIFTGFETIHLYSQLLKDVDMGNTSGMADLHALTSGLKSVVTHQTGE 399

Human   388 GIEACRMACGGHGYSHCSGLPNIYVNFTPSCTFEGENTVMMLQTARFLMKSYDQVHSG--KLVCG 450
            |||..||||||||||..|.:..||......||:||||.||:||.||:|:||.:.:.||  |.:..
 Worm   400 GIEQARMACGGHGYSMASYISEIYGIAIGGCTYEGENMVMLLQLARYLVKSVELIKSGEAKKLGP 464

Human   451 MVSYLNDLPSQRIQPQQVAVWPTMVDINSPESLTEAYKLRAARLVEIAAKNLQKEVIHRKSKEVA 515
            |||||             |......|::|......|::..|.|....|.:...|.:...:|:|:|
 Worm   465 MVSYL-------------AAKGGHPDLSSLNGYVTAFEHMARRQAWKATEKFLKLMESGESREIA 516

Human   516 WNLTSVDLVRASEAHCHYVVVKLFSEKLLKIQDKAIQAVLRSLCLL---YSLYGISQNAGDFLQG 577
            ||.::|:|.|||..|....:::.|..::.:|:|..::.||..|..|   |.|..::..|.:|
 Worm   517 WNKSTVELTRASRLHTRLFIIEAFMRRVSRIEDIPVKEVLTDLLHLHVNYELLDVATYALEF--- 578

Human   578 SIMTEPQITQVNQRVKELLTLIRSDAVALVDAFDFQDVTLGSVLGRYDGNVYENLFEWAKNSPLN 642
              |:..|:..:..::...|..||..||:|||:|...|:.|.|||||.|||||||||:|||:||||
 Worm   579 --MSSTQLDYIRDQLYLYLEKIRPSAVSLVDSFQISDMQLRSVLGRRDGNVYENLFKWAKSSPLN 641

Human   643 KAEVHESY-KHLKSLQSK 659
            |::|..|. |:|..:..|
 Worm   642 KSDVLPSVDKYLMPMMEK 659

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACOX1	NP_004026.2	AXO	3..637	CDD:173839	270/642 (42%)
acox-1.4	NP_493264.1	ACAD	13..636	CDD:447864	270/642 (42%)